Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032238-15
Application #
6180122
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Program Officer
Carter, Anthony D
Project Start
1983-07-01
Project End
2002-03-31
Budget Start
2000-04-01
Budget End
2001-03-31
Support Year
15
Fiscal Year
2000
Total Cost
$227,938
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Lawrimore, Josh; Doshi, Ayush; Friedman, Brandon et al. (2018) Geometric partitioning of cohesin and condensin is a consequence of chromatin loops. Mol Biol Cell 29:2737-2750
Suzuki, Aussie; Gupta, Amitabha; Long, Sarah K et al. (2018) A Kinesin-5, Cin8, Recruits Protein Phosphatase 1 to Kinetochores and Regulates Chromosome Segregation. Curr Biol 28:2697-2704.e3
Salmon, Edward D; Bloom, Kerry (2017) Tension sensors reveal how the kinetochore shares its load. Bioessays 39:
Ohkuni, Kentaro; Takahashi, Yoshimitsu; Fulp, Alyona et al. (2016) SUMO-Targeted Ubiquitin Ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin. Mol Biol Cell :
Tsabar, Michael; Haase, Julian; Harrison, Benjamin et al. (2016) A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere. PLoS Genet 12:e1006021
Suzuki, Aussie; Badger, Benjamin L; Haase, Julian et al. (2016) How the kinetochore couples microtubule force and centromere stretch to move chromosomes. Nat Cell Biol 18:382-92
Lawrimore, Josh; Aicher, Joseph K; Hahn, Patrick et al. (2016) ChromoShake: a chromosome dynamics simulator reveals that chromatin loops stiffen centromeric chromatin. Mol Biol Cell 27:153-66
Lawrimore, Josh; Vasquez, Paula A; Falvo, Michael R et al. (2015) DNA loops generate intracentromere tension in mitosis. J Cell Biol 210:553-64
Verdaasdonk, Jolien S; Stephens, Andrew D; Haase, Julian et al. (2014) Bending the rules: widefield microscopy and the Abbe limit of resolution. J Cell Physiol 229:132-8
Stephens, Andrew D; Quammen, Cory W; Chang, Binny et al. (2013) The spatial segregation of pericentric cohesin and condensin in the mitotic spindle. Mol Biol Cell 24:3909-19

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