Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM035679-08S1
Application #
3288696
Study Section
Genetics Study Section (GEN)
Project Start
1985-04-01
Project End
1995-06-30
Budget Start
1992-07-01
Budget End
1993-06-30
Support Year
8
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Type
Schools of Dentistry
DUNS #
605799469
City
Newark
State
NJ
Country
United States
Zip Code
07107
Irene, Carmela; Theis, James F; Gresham, David et al. (2016) Hst3p, a histone deacetylase, promotes maintenance of Saccharomyces cerevisiae chromosome III lacking efficient replication origins. Mol Genet Genomics 291:271-83
Theis, James F; Irene, Carmela; Dershowitz, Ann et al. (2010) The DNA damage response pathway contributes to the stability of chromosome III derivatives lacking efficient replicators. PLoS Genet 6:e1001227
Chang, Fujung; Theis, James F; Miller, Jeremy et al. (2008) Analysis of chromosome III replicators reveals an unusual structure for the ARS318 silencer origin and a conserved WTW sequence within the origin recognition complex binding site. Mol Cell Biol 28:5071-81
Caldwell, Julie M; Chen, Yinhuai; Schollaert, Kaila L et al. (2008) Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins. J Cell Biol 180:1073-86
Theis, James F; Dershowitz, Ann; Irene, Carmela et al. (2007) Identification of mutations that decrease the stability of a fragment of Saccharomyces cerevisiae chromosome III lacking efficient replicators. Genetics 177:1445-58
Dershowitz, Ann; Snyder, Marylynn; Sbia, Mohammed et al. (2007) Linear derivatives of Saccharomyces cerevisiae chromosome III can be maintained in the absence of autonomously replicating sequence elements. Mol Cell Biol 27:4652-63
Newlon, Carol S; Theis, James F (2002) DNA replication joins the revolution: whole-genome views of DNA replication in budding yeast. Bioessays 24:300-4
Fabiani, L; Irene, C; Aragona, M et al. (2001) A DNA replication origin and a replication fork barrier used in vivo in the circular plasmid pKD1. Mol Genet Genomics 266:326-35
Poloumienko, A; Dershowitz, A; De, J et al. (2001) Completion of replication map of Saccharomyces cerevisiae chromosome III. Mol Biol Cell 12:3317-27
Malkova, A; Signon, L; Schaefer, C B et al. (2001) RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site. Genes Dev 15:1055-60

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