Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM036260-02
Application #
3289853
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1986-01-01
Project End
1989-12-31
Budget Start
1987-01-01
Budget End
1987-12-31
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Maryland College Park
Department
Type
Earth Sciences/Resources
DUNS #
City
College Park
State
MD
Country
United States
Zip Code
20742
Wu, Chun; Dunaway-Mariano, Debra; Mariano, Patrick S (2013) Design, synthesis, and evaluation of inhibitors of pyruvate phosphate dikinase. J Org Chem 78:1910-22
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Wu, Rui; Cao, Jian; Lu, Xuefeng et al. (2008) Mechanism of 4-chlorobenzoate:coenzyme a ligase catalysis. Biochemistry 47:8026-39
Lim, Kap; Read, Randy J; Chen, Celia C H et al. (2007) Swiveling domain mechanism in pyruvate phosphate dikinase. Biochemistry 46:14845-53
Chen, Celia C H; Han, Ying; Niu, Weiling et al. (2006) Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily. Biochemistry 45:11491-504
Lin, Ying; Lusin, Jacqueline D; Ye, Dongmei et al. (2006) Examination of the structure, stability, and catalytic potential in the engineered phosphoryl carrier domain of pyruvate phosphate dikinase. Biochemistry 45:1702-11
Teplyakov, Alexey; Liu, Sijiu; Lu, Zhibing et al. (2005) Crystal structure of the petal death protein from carnation flower. Biochemistry 44:16377-84
Liu, Sijiu; Lu, Zhibing; Han, Yin et al. (2005) Crystal structures of 2-methylisocitrate lyase in complex with product and with isocitrate inhibitor provide insight into lyase substrate specificity, catalysis and evolution. Biochemistry 44:2949-62
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