Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM046779-06
Application #
2331978
Study Section
Molecular Biology Study Section (MBY)
Project Start
1992-02-01
Project End
1997-06-30
Budget Start
1997-02-01
Budget End
1997-06-30
Support Year
6
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Worcester Foundation for Biomedical Research
Department
Type
DUNS #
City
Shrewsbury
State
MA
Country
United States
Zip Code
01545
Nagaoka, K; Fujii, K; Zhang, H et al. (2016) CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene 35:2893-901
Mansur, Fernanda; Ivshina, Maria; Gu, Weifeng et al. (2016) Gld2-catalyzed 3' monoadenylation of miRNAs in the hippocampus has no detectable effect on their stability or on animal behavior. RNA 22:1492-9
Ivshina, Maria; Alexandrov, Ilya M; Vertii, Anastassiia et al. (2015) CPEB regulation of TAK1 synthesis mediates cytokine production and the inflammatory immune response. Mol Cell Biol 35:610-8
Richter, Joel D; Coller, Jeff (2015) Pausing on Polyribosomes: Make Way for Elongation in Translational Control. Cell 163:292-300
Ivshina, Maria; Lasko, Paul; Richter, Joel D (2014) Cytoplasmic polyadenylation element binding proteins in development, health, and disease. Annu Rev Cell Dev Biol 30:393-415
Udagawa, Tsuyoshi; Farny, Natalie G; Jakovcevski, Mira et al. (2013) Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med 19:1473-7
Nechama, Morris; Lin, Chien-Ling; Richter, Joel D (2013) An unusual two-step control of CPEB destruction by Pin1. Mol Cell Biol 33:48-58
Udagawa, Tsuyoshi; Swanger, Sharon A; Takeuchi, Koichi et al. (2012) Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex. Mol Cell 47:253-66
Lin, Chien-Ling; Huang, Yen-Tsung; Richter, Joel D (2012) Transient CPEB dimerization and translational control. RNA 18:1050-61
Nagaoka, Kentaro; Udagawa, Tsuyoshi; Richter, Joel D (2012) CPEB-mediated ZO-1 mRNA localization is required for epithelial tight-junction assembly and cell polarity. Nat Commun 3:675

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