Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM051953-02
Application #
2190762
Study Section
Virology Study Section (VR)
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Texas Agrilife Research
Department
Type
Schools of Earth Sciences/Natur
DUNS #
110521739
City
College Station
State
TX
Country
United States
Zip Code
77843
Li, Huiyung; Li, Changzheng; Zhou, Sufeng et al. (2013) Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid. Acta Crystallogr D Biol Crystallogr 69:617-24
Li, C-Z; Koter, M; Ye, X et al. (2010) Widespread but small-scale changes in the structural and dynamic properties of vaccinia virus poly(A) polymerase upon association with its processivity factor in solution. Biochemistry 49:6247-62
Gershon, P D (2010) Two tools for applying chromatographic retention data to the mass-based identification of peptides during hydrogen/deuterium exchange experiments by nano-liquid chromatography/matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom 24:3373-9
Li, ChangZheng; Li, Huiying; Zhou, Sufeng et al. (2009) Polymerase translocation with respect to single-stranded nucleic acid: looping or wrapping of primer around a poly(A) polymerase. Structure 17:680-9
Nikamanon, Pornpat; Pun, Elroy; Chou, Wayne et al. (2008) ""TOF2H"": a precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI approach, covering the data pipeline from spectral acquisition to HDX rate analysis. BMC Bioinformatics 9:387
Yoshizawa, Janice M; Li, Changzheng; Gershon, Paul D (2007) Saltatory forward movement of a poly(A) polymerase during poly(A) tail addition. J Biol Chem 282:19144-51
Moure, Carmen M; Bowman, Brian R; Gershon, Paul D et al. (2006) Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity. Mol Cell 22:339-49
Gershon, Paul D (2004) Studying vaccinia virus RNA processing in vitro. Methods Mol Biol 269:151-68
Johnson, L; Liu, S; Gershon, P D (2004) Molecular flexibility and discontinuous translocation of a non-templated polymerase. J Mol Biol 337:843-56
Latner, Donald R; Thompson, Joseph M; Gershon, Paul D et al. (2002) The positive transcription elongation factor activity of the vaccinia virus J3 protein is independent from its (nucleoside-2'-O-) methyltransferase and poly(A) polymerase stimulatory functions. Virology 301:64-80

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