Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052170-02
Application #
2191093
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1994-12-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Lu, Jian-Ming; Rogge, Corina E; Wu, Gang et al. (2011) Cyclooxygenase reaction mechanism of PGHS--evidence for a reversible transition between a pentadienyl radical and a new tyrosyl radical by nitric oxide trapping. J Inorg Biochem 105:356-65
Wu, Gang; Lu, Jian-Ming; van der Donk, Wilfred A et al. (2011) Cyclooxygenase reaction mechanism of prostaglandin H synthase from deuterium kinetic isotope effects. J Inorg Biochem 105:382-90
Tsai, Ah-lim; Wu, Gang; Rogge, Corina E et al. (2011) Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2. J Inorg Biochem 105:366-74
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Liu, Wen; Cao, Dazhe; Oh, Sungwhan F et al. (2006) Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases. FASEB J 20:1097-108
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