Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM053320-02
Application #
2192671
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1995-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Menichelli, Elena; Wu, Joann; Campbell, Zachary T et al. (2013) Biochemical characterization of the Caenorhabditis elegans FBF.CPB-1 translational regulation complex identifies conserved protein interaction hotspots. J Mol Biol 425:725-37
Wu, Joann; Campbell, Zachary T; Menichelli, Elena et al. (2013) A protein.protein interaction platform involved in recruitment of GLD-3 to the FBF.fem-3 mRNA complex. J Mol Biol 425:738-54
Beuck, Christine; Qu, Song; Fagg, W Samuel et al. (2012) Structural analysis of the quaking homodimerization interface. J Mol Biol 423:766-81
Campbell, Zachary T; Menichelli, Elena; Friend, Kyle et al. (2012) Identification of a conserved interface between PUF and CPEB proteins. J Biol Chem 287:18854-62
Kerkow, Donald E; Carmel, Andrew B; Menichelli, Elena et al. (2012) The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold. J Mol Biol 415:649-65
Puglisi, Joseph D; Williamson, James R (2012) Digging deep into nucleic acid structure and nucleic acid protein recognition. Curr Opin Struct Biol 22:249-50
Campbell, Zachary T; Bhimsaria, Devesh; Valley, Cary T et al. (2012) Cooperativity in RNA-protein interactions: global analysis of RNA binding specificity. Cell Rep 1:570-81
Menichelli, Elena; Edgcomb, Stephen P; Recht, Michael I et al. (2012) The structure of Aquifex aeolicus ribosomal protein S8 reveals a unique subdomain that contributes to an extremely tight association with 16S rRNA. J Mol Biol 415:489-502
Carmel, Andrew B; Wu, Joann; Lehmann-Blount, Katrina A et al. (2010) High-affinity consensus binding of target RNAs by the STAR/GSG proteins GLD-1, STAR-2 and Quaking. BMC Mol Biol 11:48
Beuck, Christine; Szymczyna, Blair R; Kerkow, Donald E et al. (2010) Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation. Structure 18:377-89

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