Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM056927-02
Application #
6181297
Study Section
Experimental Virology Study Section (EVR)
Program Officer
Rhoades, Marcus M
Project Start
1999-05-01
Project End
2004-04-30
Budget Start
2000-05-01
Budget End
2001-04-30
Support Year
2
Fiscal Year
2000
Total Cost
$248,667
Indirect Cost
Name
New York University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Vink, Elizabeth I; Lee, Sora; Smiley, James R et al. (2018) Remodeling mTORC1 Responsiveness to Amino Acids by the Herpes Simplex Virus UL46 and Us3 Gene Products Supports Replication during Nutrient Insufficiency. J Virol 92:
Burgess, Hannah M; Pourchet, Aldo; Hajdu, Cristina H et al. (2018) Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus. Mol Ther Oncolytics 8:71-81
Rubio, Rosa M; Depledge, Daniel P; Bianco, Christopher et al. (2018) RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon ?. Genes Dev 32:1472-1484
Stern-Ginossar, Noam; Thompson, Sunnie R; Mathews, Michael B et al. (2018) Translational Control in Virus-Infected Cells. Cold Spring Harb Perspect Biol :
Burgess, Hannah M; Mohr, Ian (2018) Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS. J Virol 92:
Bianco, Christopher; Mohr, Ian (2017) Restriction of Human Cytomegalovirus Replication by ISG15, a Host Effector Regulated by cGAS-STING Double-Stranded-DNA Sensing. J Virol 91:
Pourchet, Aldo; Copin, Richard; Mulvey, Matthew C et al. (2017) Shared ancestry of herpes simplex virus 1 strain Patton with recent clinical isolates from Asia and with strain KOS63. Virology 512:124-131
Linderman, Jessica A; Kobayashi, Mariko; Rayannavar, Vinayak et al. (2017) Immune Escape via a Transient Gene Expression Program Enables Productive Replication of a Latent Pathogen. Cell Rep 18:1312-1323
Vink, Elizabeth I; Smiley, James R; Mohr, Ian (2017) Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress. J Virol 91:
Mohr, Ian (2016) Closing in on the causes of host shutoff. Elife 5:

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