The overarching goal of the Colorado Adoption Project (CAP) is to assess the etiologies 01 individual difference in behavioral development. Toward this end, adoptive and non-adaptive profanes and siblings have been assessed approximately yearly from birth through their early 20's on an extensive battery of measures Including cognitive performance, academic achievement, temperament/personality, interpersonal relationships, family environment and health. The proposed two-year continuation of HD010333 will initiate an IO-year follow-up of CAP probands and siblings, now in their early 30's, and the culmination of testing of participants from infancy though early adulthood. The primary objective of this proposal is to begin to achieve a better understanding of the interplay among factors of childhood and adolescence that combine and interact to influence relevant outcomes of early adulthood pertaining Jo both intrapersonal and interpersonal well-being including those that may inform studies of later adult development, such as cognitive performance, cognitive change/decline, physical health, emotional well-being, career/job satisfaction, and interpersonal relationships. In order to achieve this objective, we will administer an extensive battery of tests and questionnaires to appropriately 272 CAP profanes and siblings. We will draw on our wide array of childhood measures to investigate factors that may mediate or moderate adult outcomes. Thus, the continuation of HD010333 will provide the foundation for a truly unique adoption study of behavioral development, spanning Infancy through early adulthood.

Public Health Relevance

This unparalleled adoption study will contribute to a better understanding of the interplay among factors of childhood and adolescence which combine and interact to influence important outcomes of adulthood, including factors which contribute to physical and emotional health. An improved understanding of genetic and environmental influences, and how they interact with early life factors to affect adult health, may contribute to improved health and well-being as well as to better health education and services.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD010333-32
Application #
7915656
Study Section
Special Emphasis Panel (ZRG1-HOP-J (02))
Program Officer
Freund, Lisa S
Project Start
1977-04-01
Project End
2012-07-31
Budget Start
2010-08-01
Budget End
2012-07-31
Support Year
32
Fiscal Year
2010
Total Cost
$399,423
Indirect Cost
Name
University of Colorado at Boulder
Department
Genetics
Type
Other Domestic Higher Education
DUNS #
007431505
City
Boulder
State
CO
Country
United States
Zip Code
80309
Ricker, Ashley A; Corley, Robin; DeFries, John C et al. (2018) Examining the influence of perceived stress on developmental change in memory and perceptual speed for adopted and nonadopted individuals. Dev Psychol 54:138-150
Hatoum, Alexander S; Rhee, Soo Hyun; Corley, Robin P et al. (2018) Etiology of Stability and Growth of Internalizing and Externalizing Behavior Problems Across Childhood and Adolescence. Behav Genet 48:298-314
Hatoum, Alexander S; Rhee, Soo Hyun; Corley, Robin P et al. (2018) Do executive functions explain the covariance between internalizing and externalizing behaviors? Dev Psychopathol 30:1371-1387
Yokoyama, Yoshie; Jelenkovic, Aline; Hur, Yoon-Mi et al. (2018) Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts. Int J Epidemiol 47:1195-1206
Piirtola, Maarit; Jelenkovic, Aline; Latvala, Antti et al. (2018) Association of current and former smoking with body mass index: A study of smoking discordant twin pairs from 21 twin cohorts. PLoS One 13:e0200140
Jelenkovic, Aline; Yokoyama, Yoshie; Sund, Reijo et al. (2018) Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project. Early Hum Dev 120:53-60
Woodward, Kerri E; Boeldt, Debra L; Corley, Robin P et al. (2018) Correlates of Positive Parenting Behaviors. Behav Genet :
Silventoinen, Karri; Jelenkovic, Aline; Latvala, Antti et al. (2017) Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts. Twin Res Hum Genet 20:395-405
Benca, Chelsie E; Derringer, Jaime L; Corley, Robin P et al. (2017) Predicting Cognitive Executive Functioning with Polygenic Risk Scores for Psychiatric Disorders. Behav Genet 47:11-24
Bogl, Leonie H; Jelenkovic, Aline; Vuoksimaa, Eero et al. (2017) Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts. Biol Sex Differ 8:14

Showing the most recent 10 out of 145 publications