Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL045954-06A2
Application #
2028589
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1992-08-01
Project End
2000-12-31
Budget Start
1997-01-15
Budget End
1997-12-31
Support Year
6
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037

  Publications

Schleef, R R; Olman, M A; Miles, L A et al. (2001) Modulating the fibrinolytic system of peripheral blood mononuclear cells with adenovirus. Hum Gene Ther 12:439-45
Chuang, J L; Schleef, R R (2001) Recombinant Semliki Forest virus enhanced plasminogen activator inhibitor 1 expression and storage in the megakaryocytic cell line MEG-01. J Cell Biochem 82:277-89
Chuang, J L; Schleef, R R (2001) Adenovirus-mediated expression and packaging of tissue-type plasminogen activator in megakaryocytic cells. Thromb Haemost 85:1079-85
Schleef, R R; Chuang, T L (2000) Protease inhibitor 10 inhibits tumor necrosis factor alpha -induced cell death. Evidence for the formation of intracellular high M(r) protease inhibitor 10-containing complexes. J Biol Chem 275:26385-9
Chuang, T L; Schleef, R R (1999) Identification of a nuclear targeting domain in the insertion between helices C and D in protease inhibitor-10. J Biol Chem 274:11194-8
Lang, I M; Moser, K M; Schleef, R R (1998) Elevated expression of urokinase-like plasminogen activator and plasminogen activator inhibitor type 1 during the vascular remodeling associated with pulmonary thromboembolism. Arterioscler Thromb Vasc Biol 18:808-15
Lang, I M; Barbas 3rd, C F; Schleef, R R (1996) Recombinant rabbit Fab with binding activity to type-1 plasminogen activator inhibitor derived from a phage-display library against human alpha-granules. Gene 172:295-8
Seiffert, D; Schleef, R R (1996) Two functionally distinct pools of vitronectin (Vn) in the blood circulation: identification of a heparin-binding competent population of Vn within platelet alpha-granules. Blood 88:552-60
Riewald, M; Morgenstern, K A; Schleef, R R (1996) Identification and characterization of the cytoplasmic antiproteinase (CAP) in human platelets. Evidence for the interaction of CAP with endogenous platelet proteins. J Biol Chem 271:7160-7
Lang, I M; Chuang, T L; Barbas 3rd, C F et al. (1996) Purification of storage granule protein-23. A novel protein identified by phage display technology and interaction with type I plasminogen activator inhibitor. J Biol Chem 271:30126-35

Showing the most recent 10 out of 23 publications