Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL046350-07
Application #
2222846
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1993-06-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Illinois at Chicago
Department
Pharmacology
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

Xu, Jingsong; Gao, Xiao-Pei; Ramchandran, Ramaswamy et al. (2008) Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins. Nat Immunol 9:880-6
Van Driessche, Willy; Kreindler, James L; Malik, Asrar B et al. (2007) Interrelations/cross talk between transcellular transport function and paracellular tight junctional properties in lung epithelial and endothelial barriers. Am J Physiol Lung Cell Mol Physiol 293:L520-4
Gao, Xiao-Pei; Zhu, Xiangdong; Fu, Jian et al. (2007) Blockade of class IA phosphoinositide 3-kinase in neutrophils prevents NADPH oxidase activation- and adhesion-dependent inflammation. J Biol Chem 282:6116-25
Miyawaki-Shimizu, Kayo; Predescu, Dan; Shimizu, Jun et al. (2006) siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. Am J Physiol Lung Cell Mol Physiol 290:L405-13
Garrean, Sean; Gao, Xiao-Pei; Brovkovych, Victor et al. (2006) Caveolin-1 regulates NF-kappaB activation and lung inflammatory response to sepsis induced by lipopolysaccharide. J Immunol 177:4853-60
Ong, Evan; Gao, Xiao-Pei; Predescu, Dan et al. (2005) Role of phosphatidylinositol 3-kinase-gamma in mediating lung neutrophil sequestration and vascular injury induced by E. coli sepsis. Am J Physiol Lung Cell Mol Physiol 289:L1094-103
Fu, Jian; Naren, Anjaparavanda P; Gao, Xiaopei et al. (2005) Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression. J Biol Chem 280:3178-84
Zhou, Ximing; Gao, Xiao-Pei; Fan, Jie et al. (2005) LPS activation of Toll-like receptor 4 signals CD11b/CD18 expression in neutrophils. Am J Physiol Lung Cell Mol Physiol 288:L655-62
Gao, Xiao-Pei; Liu, Qinghui; Broman, Michael et al. (2005) Inactivation of CD11b in a mouse transgenic model protects against sepsis-induced lung PMN infiltration and vascular injury. Physiol Genomics 21:230-42
Siddiqui, Shahid S; Siddiqui, Zeba K; Malik, Asrar B (2004) Albumin endocytosis in endothelial cells induces TGF-beta receptor II signaling. Am J Physiol Lung Cell Mol Physiol 286:L1016-26

Showing the most recent 10 out of 67 publications