Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051323-03
Application #
2228005
Study Section
Physiology Study Section (PHY)
Project Start
1994-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Fuster, Daniel; Moe, Orson W; Hilgemann, Donald W (2008) Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models with 2Na/2H stoichiometry. J Gen Physiol 132:465-80
Yaradanakul, Alp; Wang, Tzu-Ming; Lariccia, Vincenzo et al. (2008) Massive Ca-induced membrane fusion and phospholipid changes triggered by reverse Na/Ca exchange in BHK fibroblasts. J Gen Physiol 132:29-50
Wang, Tzu-Ming; Hilgemann, Donald W (2008) Ca-dependent nonsecretory vesicle fusion in a secretory cell. J Gen Physiol 132:51-65
Hilgemann, Donald W (2007) Local PIP(2) signals: when, where, and how? Pflugers Arch 455:55-67
Yaradanakul, Alp; Hilgemann, Donald W (2007) Unrestricted diffusion of exogenous and endogenous PIP(2 )in baby hamster kidney and Chinese hamster ovary cell plasmalemma. J Membr Biol 220:53-67
Yaradanakul, Alp; Feng, Siyi; Shen, Chengcheng et al. (2007) Dual control of cardiac Na+ Ca2+ exchange by PIP(2): electrophysiological analysis of direct and indirect mechanisms. J Physiol 582:991-1010
Shen, Chengcheng; Lin, Mei-Jung; Yaradanakul, Alp et al. (2007) Dual control of cardiac Na+ Ca2+ exchange by PIP(2): analysis of the surface membrane fraction by extracellular cysteine PEGylation. J Physiol 582:1011-26
Hilgemann, Donald W (2007) On the physiological roles of PIP(2) at cardiac Na+ Ca2+ exchangers and K(ATP) channels: a long journey from membrane biophysics into cell biology. J Physiol 582:903-9
Hilgemann, Donald W; Yaradanakul, Alp; Wang, Yong et al. (2006) Molecular control of cardiac sodium homeostasis in health and disease. J Cardiovasc Electrophysiol 17 Suppl 1:S47-S56
Fuster, Daniel; Moe, Orson W; Hilgemann, Donald W (2004) Lipid- and mechanosensitivities of sodium/hydrogen exchangers analyzed by electrical methods. Proc Natl Acad Sci U S A 101:10482-7

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