Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL055301-01A1
Application #
2233860
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1996-07-15
Project End
2000-06-30
Budget Start
1996-07-15
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Goncharova, Elena A; Goncharov, Dmitry A; Damera, Gautam et al. (2009) Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis. Mol Pharmacol 76:766-77
Goncharova, Elena A; Goncharov, Dmitry A; Chisolm, Amelia et al. (2008) Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation. Mol Pharmacol 73:778-88
Kang, Bit-Na; Tirumurugaan, K G; Deshpande, Deepak A et al. (2006) Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids. FASEB J 20:1000-2
Huang, Chien-Da; Ammit, Alaina J; Tliba, Omar et al. (2005) G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells. J Biomed Sci 12:763-76
Krymskaya, Vera P; Goncharova, Elena A; Ammit, Alaina J et al. (2005) Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration. FASEB J 19:428-30
Deshpande, Deepak A; White, Thomas A; Dogan, Soner et al. (2005) CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 288:L773-88
Ali, Hydar; Panettieri Jr, Reynold A (2005) Anaphylatoxin C3a receptors in asthma. Respir Res 6:19
Thangam, E Berla; Venkatesha, Rampura T; Zaidi, Asifa K et al. (2005) Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact. FASEB J 19:798-800
York, Brian; Lou, Dingyuan; Panettieri Jr, Reynold A et al. (2005) Cross-talk between tuberin, calmodulin, and estrogen signaling pathways. FASEB J 19:1202-4
Kang, Bit Na; Deshpande, Deepak A; Tirumurugaan, K G et al. (2005) Adenoviral mediated anti-sense CD38 attenuates TNF-alpha-induced changes in calcium homeostasis of human airway smooth muscle cells. Can J Physiol Pharmacol 83:799-804

Showing the most recent 10 out of 62 publications