Myocardial Integrins and Ventricular Remodeling

Janicki, Joseph S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 1R01HL059981-01A1
• Application #: 2762472
• Study Section: Cardiovascular and Pulmonary Research A Study Section (CVA)
• Project Start: 1999-01-11
• Project End: 2002-12-31
• Budget Start: 1999-01-11
• Budget End: 1999-12-31
• Support Year: 1
• Fiscal Year: 1999

Institution

• Name: Auburn University at Auburn
• Department: Veterinary Sciences
• Type: Schools of Veterinary Medicine
• City: Auburn University
• State: AL
• Country: United States
• Zip Code: 36849

Publications

Janicki, Joseph S; Brower, Gregory L; Levick, Scott P (2015) The emerging prominence of the cardiac mast cell as a potent mediator of adverse myocardial remodeling. Methods Mol Biol 1220:121-39

Li, Jianping; Jubair, Shaiban; Janicki, Joseph S (2015) Estrogen inhibits mast cell chymase release to prevent pressure overload-induced adverse cardiac remodeling. Hypertension 65:328-34

Stewart Jr, James A; Gardner, Jason D; Brower, Gregory L et al. (2014) Temporal changes in integrin-mediated cardiomyocyte adhesion secondary to chronic cardiac volume overload in rats. Am J Physiol Heart Circ Physiol 306:H101-8

Janicki, Joseph S; Spinale, Francis G; Levick, Scott P (2013) Gender differences in non-ischemic myocardial remodeling: are they due to estrogen modulation of cardiac mast cells and/or membrane type 1 matrix metalloproteinase. Pflugers Arch 465:687-97

Jobe, Lynetta J; Melendez, Giselle C; Levick, Scott P et al. (2009) TNF-alpha inhibition attenuates adverse myocardial remodeling in a rat model of volume overload. Am J Physiol Heart Circ Physiol 297:H1462-8

Janicki, Joseph S; Brower, Gregory L; Gardner, Jason D et al. (2006) Cardiac mast cell regulation of matrix metalloproteinase-related ventricular remodeling in chronic pressure or volume overload. Cardiovasc Res 69:657-65

Brower, Gregory L; Gardner, Jason D; Forman, Mary F et al. (2006) The relationship between myocardial extracellular matrix remodeling and ventricular function. Eur J Cardiothorac Surg 30:604-10

Morales, Mary O; Price, Robert L; Goldsmith, Edie C (2005) Expression of Discoidin Domain Receptor 2 (DDR2) in the developing heart. Microsc Microanal 11:260-7

Janicki, Joseph S; Brower, Gregory L; Gardner, Jason D et al. (2004) The dynamic interaction between matrix metalloproteinase activity and adverse myocardial remodeling. Heart Fail Rev 9:33-42

Goldsmith, Edie C; Hoffman, Adam; Morales, Mary O et al. (2004) Organization of fibroblasts in the heart. Dev Dyn 230:787-94