Research suggests that 4 - 23% of the seriously mentally ill (SMI) are infected with the human immunodeficiency virus (HIV). The long-term aim of the proposed research is to reduce the prevalence of HIV infection among SMI adults who receive outpatient psychiatric care.
The specific aims are (1) to conduct formative research regarding HIV-related risk behavior among the SMI; (2) to refine, implement, and evaluate an HIV-risk reduction program with the SMI; and (3) to use Fisher and Fisher's (1992) Information-Motivation-Behavioral Skills model to account for variability in HIV-related risk behavior in the SMI. The proposed research begins with 6 months of formative research; focus groups and individual qualitative interviews will be conducted with 25 men and 25 women. Based upon prior pilot and proposed formative work, a theoretically-based, culturally- and clinically-sensitive, HIV risk reduction intervention for the SMI will be implemented with 216 men and 216 women. Participants will be randomly assigned to (a) an HIV Risk Reduction program (HIV), (b) a Substance Use Reduction (SUR), or (c) a Standard Care (Control) Condition. Assessments made at baseline, post-intervention, and at 3- and 6-month follow-ups will measure HIV-related information, motivation, behavioral skills, and sexual practices. We hypothesize that, relative to participants assigned to the SUR and Control conditions, participants in the HIV intervention will increase HIV-relevant (a) information, (b) motivation, (c) behavioral skills; and decrease (d) the frequency of risky sexual practices. We hypothesize further that (e) participants in the HIV condition will redeem coupons for condoms and seek voluntary HIV-antibody testing at a greater rate than will participants in the SUR and Control conditions; (f) independent of treatment condition and substance use behavior, HIV preventive behavior at time n + 1 (e.g., 3-month follow-up) will be a function of individuals' information about the transmission and prevention of HIV infection, motivation to engage in HIV prevention, and behavioral skills for performing the specific acts involved in prevention at time n (e.g., post-test); and (g) information and motivation will be mediated by behavioral skills to influence preventive behavior. The intent of this research is to develop a risk reduction program that can be used by community-based mental health organizations to reduce the risk of HIV infection among the SMI.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Research Project (R01)
Project #
Application #
Study Section
Psychobiological, Biological, and Neurosciences Subcommittee (MHAI)
Program Officer
Stoff, David M
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Syracuse University
Schools of Arts and Sciences
United States
Zip Code
Fielder, Robyn L; Carey, Michael P (2010) Predictors and consequences of sexual ""hookups"" among college students: a short-term prospective study. Arch Sex Behav 39:1105-19
Chandra, Prabha S; Satyanarayana, Veena A; Carey, Michael P (2009) Women reporting intimate partner violence in India: associations with PTSD and depressive symptoms. Arch Womens Ment Health 12:203-9
Rao, Min; Varghese, Tomy; Madsen, Ernest L (2008) Shear strain imaging using shear deformations. Med Phys 35:412-23
Jaworski, Beth C; Carey, Michael P (2007) Development and psychometric evaluation of a self-administered questionnaire to measure knowledge of sexually transmitted diseases. AIDS Behav 11:557-74
Varma, Deepthi; Chandra, Prabha S; Thomas, Tinku et al. (2007) Intimate partner violence and sexual coercion among pregnant women in India: relationship with depression and post-traumatic stress disorder. J Affect Disord 102:227-35
Carey, Michael P; Ravi, V; Chandra, Prabha S et al. (2007) Prevalence of HIV, Hepatitis B, syphilis, and chlamydia among adults seeking treatment for a mental disorder in southern India. AIDS Behav 11:289-97
Vanable, Peter A; Carey, Michael P; Carey, Kate B et al. (2007) Differences in HIV-related knowledge, attitudes, and behavior among psychiatric outpatients with and without a history of a sexually transmitted infection. J Prev Interv Community 33:79-94
Senn, Theresa E; Carey, Michael P; Vanable, Peter A et al. (2007) Characteristics of sexual abuse in childhood and adolescence influence sexual risk behavior in adulthood. Arch Sex Behav 36:637-45
Senn, Theresa E; Carey, Michael P; Vanable, Peter A et al. (2007) Even if you build it, we may not come: correlates of non-attendance at a sexual risk reduction workshop for STD clinic patients. AIDS Behav 11:864-71
Carey, Michael P; Ravi, V; Chandra, Prabha S et al. (2006) Screening for sexually transmitted infections at a DeAddictions service in south India. Drug Alcohol Depend 82:127-34

Showing the most recent 10 out of 56 publications