Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS032385-02
Application #
2270536
Study Section
Endocrinology Study Section (END)
Program Officer
Kitt, Cheryl A
Project Start
1995-08-04
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Pharmacology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Bulgari, Dinara; Jha, Anupma; Deitcher, David L et al. (2018) Myopic (HD-PTP, PTPN23) selectively regulates synaptic neuropeptide release. Proc Natl Acad Sci U S A 115:1617-1622
Bulgari, Dinara; Deitcher, David L; Levitan, Edwin S (2017) Loss of Huntingtin stimulates capture of retrograde dense-core vesicles to increase synaptic neuropeptide stores. Eur J Cell Biol 96:402-406
Tao, Juan; Bulgari, Dinara; Deitcher, David L et al. (2017) Limited distal organelles and synaptic function in extensive monoaminergic innervation. J Cell Sci 130:2520-2529
Rao, Kavitha; Stone, Michelle C; Weiner, Alexis T et al. (2016) Spastin, atlastin, and ER relocalization are involved in axon but not dendrite regeneration. Mol Biol Cell 27:3245-3256
Cavolo, Samantha L; Bulgari, Dinara; Deitcher, David L et al. (2016) Activity Induces Fmr1-Sensitive Synaptic Capture of Anterograde Circulating Neuropeptide Vesicles. J Neurosci 36:11781-11787
Roland, Bartholomew P; Zeccola, Alison M; Larsen, Samantha B et al. (2016) Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics. PLoS Genet 12:e1005941
Cavolo, Samantha L; Zhou, Chaoming; Ketcham, Stephanie A et al. (2015) Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles. Mol Biol Cell 26:2664-72
Wong, Man Yan; Cavolo, Samantha L; Levitan, Edwin S (2015) Synaptic neuropeptide release by dynamin-dependent partial release from circulating vesicles. Mol Biol Cell 26:2466-74
Li, Long; Tian, Xiaolin; Zhu, Mingwei et al. (2014) Drosophila Syd-1, liprin-?, and protein phosphatase 2A B' subunit Wrd function in a linear pathway to prevent ectopic accumulation of synaptic materials in distal axons. J Neurosci 34:8474-87
James, Rebecca E; Hoover, Kendall M; Bulgari, Dinara et al. (2014) Crimpy enables discrimination of presynaptic and postsynaptic pools of a BMP at the Drosophila neuromuscular junction. Dev Cell 31:586-98

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