. The most recent UNAIDS estimates of the global burden of HIV are that 36.9 million people are living with HIV-1 infection worldwide, with 69.4% of these residing in sub-Saharan Africa. Markedly, three in four new infections in sub-Saharan Africa are among girls aged 15?19 years and young women aged 15?24 years are twice as likely to be living with HIV than men that age. Further, a striking difference exists between the east/southern and the west/central regions of sub-Saharan Africa, with reductions in AIDS-related deaths since 2010 of 42% and 24%, respectively. Clearly, much work remains in terms of training local physicians and scientists in the diagnosis, treatment, and management of individuals with HIV-1 infection; conducting implementation science to determine the most cost-effective use of financial and human resources; and ensuring evidence-informed public health policy and programming to reduce disparities in the AIDS response across Africa?s sub-regions. Despite treatment likely having contributed to slowing HIV transmission, HIV prevention remains critical to stem the tide of HIV. In fact, a second AIDS pandemic in the next 12 years is predicted due to 1) changing demographics in Africa with increasing numbers of youth, 2) increasing transmitted viral drug resistance, and 3) increased cost and limited availability of 2nd and 3rd line treatment regimens. Taken together, these factors suggest that the total number of people living with AIDS may increase by 2 million/year to reach a staggering 50 million worldwide by 2030. Since 2007, 13 successful annual INTEREST Conferences, known as the ?African CROI?, have brought together scientists involved in HIV diagnosis and treatment, pathogenesis, and prevention research in resource-limited settings in Africa to share pivotal findings, promote collaboration, and transfer experiences across several fields and many continents. Planning and organization of the 2020 INTEREST Conference will be overseen by the Amsterdam Institute of Global Health and Development. Catherine Hankins MD PhD chairs INTEREST?s International Conference Committee (ICC) and is the Scientific Chair of INTEREST. The organizers of the 2020 INTEREST Conference will pursue the following objectives: 1) To provide cutting-edge knowledge in the fields of diagnosis and treatment, pathogenesis, and prevention of HIV-1 for adults, including the elderly; adolescents; and children living with HIV in Africa, in order to contribute to achieving the 90-90-90 viral suppression goal and to preventing a second great pandemic. 2) To foster new research interactions among leading investigators and those who represent the potential future scientific leadership for health care and research on the African continent.

Public Health Relevance

. Currents efforts are ramping up to control local HIV epidemics in Africa by providing effective treatment and prevention strategies for people living with HIV-1 infection. The 2020 INTEREST Conference will focus on the scientific training and capacity building of young African clinicians and scientists whose scope of work is to implement and evaluate evidence-based: 1) early diagnosis and clinical care for HIV-1 infection, 2) effective antiretroviral treatment, and 3) tailored prevention strategies. Moreover, the three-day INTEREST conference, which profiles state-of-the-art science, will support the career development of young African clinicians and scientists by: 1) fostering local and international scientific exchange; 2) providing opportunities to present their results; and 3) facilitating their close interaction with scientific peers and invited international experts to explore career choices and opportunities for scientific collaboration.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Conference (R13)
Project #
1R13AI152885-01
Application #
10012378
Study Section
Special Emphasis Panel (ZAI1)
Program Officer
Gutierrez, Martin
Project Start
2020-03-06
Project End
2021-02-28
Budget Start
2020-03-06
Budget End
2021-02-28
Support Year
1
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Duke University
Department
Surgery
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705