To strengthen and enhance our existing research and academic support activities by implementing an interdisciplinary early inquiry-based group research program and a collaborative intervention and retention program in the School of Arts and Sciences that will be designated as the """"""""RISE for SUCCESS Program"""""""" (SUCCESS refers to Securing Undergraduate Competencies in gateway Courses through Enhanced Study and mentoring Support). The measurable outcomes for this aim and objective are to: 1) increase the current 85% retention rate to 90% between the freshman and sophomore years among RISE participants;2) increase the retention for all science majors from the current campus-wide retention rate of 73% (all major areas) to 80%;and 3) increase external internship participation by RISE participants from the current 43% to 100%. To increase students'knowledge of graduate degree programs and biomedical careers by integrating a """"""""biomedical careers focused"""""""" curriculum into our existing seminar courses. The measurable outcome for this aim and objective is to have an increase in the graduate school application rate from the current 10% to 100% for participating RISE undergraduates. To recruit graduate students and implement a formal mentoring program in the biomedical sciences. The measurable outcomes are to: 1) increase the current doctoral program completion rate among RISE graduate participants from 77% to 85% over the next five years;and 2) to increase the number of RISE doctoral students to fifteen (15). We will continue to provide high quality research experiences and provide support activities to improve scientific writing skills. The measurable outcomes are: 1) all RISE graduate students will be assigned to active research labs with well-published research mentors by the beginning of their second year;2) to double the RISE graduate students'overall publications average of 0.25 publications/student/year to 0.5 publications/student/year;and 3) to increase the number of second-year graduate RISE participants who apply for the National Research Service Award and other doctoral fellowships to a 100% application rate. To require graduate student participation in academic and career development activities that will be offered during the grant period. Topics in Biomedical Research and Careers will be integrated into our existing seminar classes offered once a year. The measurable outcome is to improve from the current 75% to 95% entrance rate into postdoctoral and/or biomedical positions.

Public Health Relevance

To provide robust research programs in the biomedical sciences with qualified, energetic, committed and focused researchers and faculty to enhance Clark Atlanta University's successful track records in research training of both undergraduate and graduate students. These students will go on to pursue terminal degrees and acquire careers in the biomedical fields.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
5R25GM060414-10
Application #
8232005
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Broughton, Robin Shepard
Project Start
1999-09-30
Project End
2015-01-31
Budget Start
2012-02-01
Budget End
2013-01-31
Support Year
10
Fiscal Year
2012
Total Cost
$1,087,235
Indirect Cost
$64,847
Name
Clark Atlanta University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
065325177
City
Atlanta
State
GA
Country
United States
Zip Code
30314
Scarlett, Kisha A; White, El-Shaddai Z; Coke, Christopher J et al. (2018) Agonist-induced CXCR4 and CB2 Heterodimerization Inhibits G?13/RhoA-mediated Migration. Mol Cancer Res 16:728-739
Burton, Liza J; Henderson, Veronica; Liburd, Latiffa et al. (2017) Snail transcription factor NLS and importin ?1 regulate the subcellular localization of Cathepsin L and Cux1. Biochem Biophys Res Commun 491:59-64
Morton, Derrick J; Patel, Divya; Joshi, Jugal et al. (2017) ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation. Oncotarget 8:2536-2549
Kong, Gui-Mei; Yu, Min; Gu, Zhongping et al. (2017) Selective small-chemical inhibitors of protein arginine methyltransferase 5 with anti-lung cancer activity. PLoS One 12:e0181601
Nichols, India S; Jones, Mary I; Okere, Chuma et al. (2017) Nitrergic neurons of the dorsal raphe nucleus encode information about stress duration. PLoS One 12:e0187071
Coke, Christopher J; Scarlett, Kisha A; Chetram, Mahandranauth A et al. (2016) Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression. J Biol Chem 291:9991-10005
Vo, Baohan T; Morton Jr, Derrick; Komaragiri, Shravan et al. (2013) TGF-? effects on prostate cancer cell migration and invasion are mediated by PGE2 through activation of PI3K/AKT/mTOR pathway. Endocrinology 154:1768-79
Don-Salu-Hewage, Ayesha S; Chan, Siu Yuen; McAndrews, Kathleen M et al. (2013) Cysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cells. PLoS One 8:e57194
Shashikala, H B Mihiri; Nicolas, Chantel I; Wang, Xiao-Qian (2012) Tunable Doping in Graphene by Light-Switchable Molecules. J Phys Chem C Nanomater Interfaces 116:26102-26105
Chetram, Mahandranauth A; Odero-Marah, Valerie; Hinton, Cimona V (2011) Loss of PTEN permits CXCR4-mediated tumorigenesis through ERK1/2 in prostate cancer cells. Mol Cancer Res 9:90-102

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