Application): Hunter College proposes to continue the traditions and expand the objectives of its 17-year-old MBRS program which has produced approximately 30 Ph.D.s from its undergraduate and graduate ranks (15 are in progress). Three developmental activities are proposed: (1) The existing undergraduate and graduate student research training program will be continued, expanded, and improved. At both the undergraduate and graduate student level it provides an intensive research experience in a lab engaged in nationally funded, competitive, state-of-the-art biomedical science research. At the undergraduate level it also involves intensive mentoring by a faculty member and other enrichment activities intended to enhance scientific performance and to inspire and motive students to seek advanced degrees in science and research careers. This activity also includes establishment of a centralized Office for Minority Programs in science at Hunter College and support for construction of a new undergraduate physics laboratory. 2) A program for development of new courses in the sciences and for instructional technology development will be implemented. This will include establishment of new courses, adoption of computer technologies in classroom lectures, distance learning, and incorporation of the World Wide Web into curricula. 3) The Hunter College Undergraduate Student Summer Research Training Program, which provides a summer research experience for non-Hunter minority students, will be supported and expanded. The MBRS RISE goals of these developmental activities are to increase the number of underrepresented minorities entering biomedical research careers (1 and 3) and to enhance science learning and the number of science majors (both minority and majority students) at Hunter College. A number of specific objectives of this program are detailed in the evaluation plan. The most important include increasing entrance into Ph.D. programs of undergraduates who are underrepresented in science from 31 percent to 50 percent (from 1.7 to 2.7 students per year) and increasing the number of Ph.D.s awarded to students underrepresented in science in Hunter graduate programs by 25 percent (from 0.82 to 1.0 students per year) (activity 1). The number of science majors at Hunter College will be increased by 20 percent in four years, from 1,192 to 1,430 students (activity 2).

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Education Projects (R25)
Project #
Application #
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Zlotnik, Hinda
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Hunter College
Schools of Arts and Sciences
New York
United States
Zip Code
Farley, Christopher; Aggarwal, Amit; Singh, Sunaina et al. (2018) A Structural Model of Nitro-Porphyrin Dyes Based on Spectroscopy and Density Functional Theory. J Comput Chem 39:1129-1142
Luine, Victoria; Serrano, Peter; Frankfurt, Maya (2018) Rapid effects on memory consolidation and spine morphology by estradiol in female and male rodents. Horm Behav :
Hernández, Yözen; Bernstein, Rocky; Pagan, Pedro et al. (2018) BpWrapper: BioPerl-based sequence and tree utilities for rapid prototyping of bioinformatics pipelines. BMC Bioinformatics 19:76
Jean-Louis, Teneka; Rockwell, Patricia; Figueiredo-Pereira, Maria E (2018) Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by ?- and ?-secretases: relevance to Alzheimer's disease. Neurobiol Aging 62:130-145
Fonseca, Danae; Baquero, Jorge; Murphy, Michael R et al. (2018) mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response. Mol Cell Biol 38:
Avila, Jorge A; Zanca, Roseanna M; Shor, Denis et al. (2018) Chronic voluntary oral methamphetamine induces deficits in spatial learning and hippocampal protein kinase Mzeta with enhanced astrogliosis and cyclooxygenase-2 levels. Heliyon 4:e00509
Corwin, Chuhyon; Nikolopoulou, Anastasia; Pan, Allen L et al. (2018) Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets. J Neuroinflammation 15:272
Di, Lia; Wan, Zhenmao; Akther, Saymon et al. (2018) Genotyping and Quantifying Lyme Pathogen Strains by Deep Sequencing of the Outer Surface Protein C (ospC) Locus. J Clin Microbiol 56:
Valderrama, Jorge; Miranda, Regina (2017) Early life stress predicts negative urgency through brooding, depending on 5-HTTLPR genotype: A pilot study with 6-month follow-up examining suicide ideation. Psychiatry Res 258:481-487
Avila, Jorge A; Alliger, Amber A; Carvajal, Brigett et al. (2017) Estradiol rapidly increases GluA2-mushroom spines and decreases GluA2-filopodia spines in hippocampus CA1. Hippocampus 27:1224-1229

Showing the most recent 10 out of 85 publications