Bioethics is a nascent discipline in South Africa and in Africa in general, and the teaching of bioethics remains largely unaddressed in the majority of Africa's medical schools. As a result, researchers and both professional and lay members of institutional review boards are poorly trained in the basic concepts of bioethics. This leaves many patients and animals in Africa vulnerable to exploitation by medical research. The South African Research Ethics Training Initiative (SARETI) plans to address this in a multi-disciplinary, multi-center, national co-operative effort by three key and numerous other role players. The University of Pretoria with its Faculty of Medicine, School of Health Systems and Public Health, and its Law Faculty which includes the Centre for Human Rights, proposes to form a consortium with the University of South Africa's Law Faculty, the University of Natal's School of Psychology and its Unilever Centre for Comparative and Applied Ethics, and the Africa Centre for Population Studies and Reproductive Health (a Wellcome Trust funded centre associated with the University of Natal) to provide innovative training in health research ethics for the sub-Saharan region of Africa. The main educational component of this program focuses on a modular Master's degree in research ethics in which the modules will also be used as """"""""stand alone"""""""" courses for researchers and IRB members who do not have the time to attend full-time for a Master's degree, and as a """"""""diploma"""""""" course which does not carry a dissertation requirement. A second, but equally important, component is the creation of opportunities for South African staff in the collaborating institutions to advance their own training in research ethics, centered around the modules they teach. The smaller components of the program include: annual meetings of advisory board, quarterly meetings of the collaborating staff, arranging an annual research ethics symposium for the sub- Saharan region in Africa, and, in the last two years, producing 6 modules on compact disc and on the web-sites of the participating institutions.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
Education Projects (R25)
Project #
1R25TW001599-01
Application #
6313674
Study Section
Special Emphasis Panel (ZRG1-SNEM-4 (04))
Program Officer
Sina, Barbara J
Project Start
2000-09-30
Project End
2002-09-29
Budget Start
2000-09-30
Budget End
2001-09-29
Support Year
1
Fiscal Year
2000
Total Cost
$50,000
Indirect Cost
Name
University of Pretoria
Department
Type
DUNS #
City
Pretoria
State
Country
South Africa
Zip Code
0002
Adewale, Babatunde; Schoeman, Lizette; Roussouw, Theresa (2015) Knowledge and perceptions of research participants in Nigeria about clinical trials. Indian J Med Ethics 12:196-8
Silaigwana, Blessing; Wassenaar, Douglas (2015) Biomedical Research Ethics Committees in sub-Saharan Africa: a collective review of their structure, functioning, and outcomes. J Empir Res Hum Res Ethics 10:169-84
Kombe, Francis; Anunobi, Eucharia Nkechinyere; Tshifugula, Nyanyukweni Pandeni et al. (2014) Promoting research integrity in Africa: an African voice of concern on research misconduct and the way forward. Dev World Bioeth 14:158-66
Okonta, Patrick I; Rossouw, Theresa (2014) Misconduct in research: a descriptive survey of attitudes, perceptions and associated factors in a developing country. BMC Med Ethics 15:25
Omondi Aduda, Dickens S; Mkhize, Nhlanhla (2014) Ethical issues evolving from patients' perspectives on compulsory screening for syphilis and voluntary screening for cervical cancer in Kenya. BMC Med Ethics 15:27
Ndebele, Paul; Wassenaar, Douglas; Masiye, Francis et al. (2014) Trial participants' understanding of randomization, double-blinding, and placebo use in low literacy populations: findings from a study conducted within a microbicide trial in Malawi. J Empir Res Hum Res Ethics 9:2-10
Okonta, Patrick; Rossouw, Theresa (2013) Prevalence of scientific misconduct among a group of researchers in Nigeria. Dev World Bioeth 13:149-57
Ndebele, Paul M; Wassenaar, Douglas; Munalula, Esther et al. (2012) Improving understanding of clinical trial procedures among low literacy populations: an intervention within a microbicide trial in Malawi. BMC Med Ethics 13:29
Wassenaar, Douglas R; Ramjee, Gita (2009) A developing country response to Lavery et al. ""In global health research, is it legitimate to stop clinical trials early on account of their opportunity costs?"". BMC Med Ethics 10:16