Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37AG000425-27S1
Application #
3479922
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1978-07-01
Project End
1992-06-30
Budget Start
1992-04-15
Budget End
1992-06-30
Support Year
27
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Koh, Jin-Ho; Hancock, Chad R; Terada, Shin et al. (2017) PPAR? Is Essential for Maintaining Normal Levels of PGC-1? and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise. Cell Metab 25:1176-1185.e5
Leong, Josiah K; Pestilli, Franco; Wu, Charlene C et al. (2016) White-Matter Tract Connecting Anterior Insula to Nucleus Accumbens Correlates with Reduced Preference for Positively Skewed Gambles. Neuron 89:63-9
Kim, Sang Hyun; Koh, Jin Ho; Higashida, Kazuhiko et al. (2015) PGC-1? mediates a rapid, exercise-induced downregulation of glycogenolysis in rat skeletal muscle. J Physiol 593:635-43
Kim, Sang Hyun; Asaka, Meiko; Higashida, Kazuhiko et al. (2013) ?-Adrenergic stimulation does not activate p38 MAP kinase or induce PGC-1? in skeletal muscle. Am J Physiol Endocrinol Metab 304:E844-52
Higashida, Kazuhiko; Kim, Sang Hyun; Jung, Su Ryun et al. (2013) Effects of resveratrol and SIRT1 on PGC-1? activity and mitochondrial biogenesis: a reevaluation. PLoS Biol 11:e1001603
Holloszy, John O (2013) ""Deficiency"" of mitochondria in muscle does not cause insulin resistance. Diabetes 62:1036-40
Han, Dong-Ho; Kim, Sang Hyun; Higashida, Kazuhiko et al. (2012) Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats. Metabolism 61:1615-21
Holloszy, John O (2011) Regulation of mitochondrial biogenesis and GLUT4 expression by exercise. Compr Physiol 1:921-40
Gan, Zhenji; Burkart-Hartman, Eileen M; Han, Dong-Ho et al. (2011) The nuclear receptor PPAR?/? programs muscle glucose metabolism in cooperation with AMPK and MEF2. Genes Dev 25:2619-30
Han, Dong-Ho; Hancock, Chad R; Jung, Su Ryun et al. (2011) Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance. PLoS One 6:e19739

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