Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI024272-04
Application #
3481287
Study Section
Immunobiology Study Section (IMB)
Project Start
1986-07-01
Project End
1991-06-30
Budget Start
1989-07-01
Budget End
1990-06-30
Support Year
4
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Brandeis University
Department
Type
Organized Research Units
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
02454
Haba, S; Nisonoff, A (1996) In vitro investigation of factors influencing IgE synthesis. J Immunol Methods 198:133-43
Nisonoff, A; Oliveira, T M; Sharon, J (1993) An analysis of idiotype expression in a high-affinity, somatically mutated variant of a germline-encoded anti-p-azobenzenearsonate antibody. Int Immunol 5:1-9
Lascombe, M B; Alzari, P M; Poljak, R J et al. (1992) Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody. Proc Natl Acad Sci U S A 89:9429-33
Rath, S; Nisonoff, A; Selsing, E et al. (1991) B cell abnormalities induced by a mu Ig transgene extend to L chain isotype usage. J Immunol 146:2841-6
Nisonoff, A (1991) Idiotypes: concepts and applications. J Immunol 147:2429-38
Haba, S; Nisonoff, A (1991) Induction of tolerance to syngeneic IgE in neonatal mice. J Immunol 146:807-11
Haba, S; Nisonoff, A (1990) Inhibition of IgE synthesis by anti-IgE: role in long-term inhibition of IgE synthesis by neonatally administered soluble IgE. Proc Natl Acad Sci U S A 87:3363-7
Haba, S; Lascombe, M B; Poljak, R J et al. (1989) Structure of idiotopes associated with antiphenylarsonate antibodies expressing an intrastrain crossreactive idiotype. J Exp Med 170:1075-90
Rath, S; Durdik, J; Gerstein, R M et al. (1989) Quantitative analysis of idiotypic mimicry and allelic exclusion in mice with a mu Ig transgene. J Immunol 143:2074-80
Haba, S; Nisonoff, A (1988) Immunological responsiveness of neonatal A/J mice to isotypic determinants of syngeneic IgE. J Exp Med 168:713-24

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