Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA020329-13
Application #
3481852
Study Section
Experimental Therapeutics Subcommittee 2 (ET)
Project Start
1976-09-01
Project End
1988-08-31
Budget Start
1988-06-01
Budget End
1988-08-31
Support Year
13
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Rochester
Department
Type
School of Medicine & Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Laderoute, K R; Mendonca, H L; Calaoagan, J M et al. (1999) Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protei J Biol Chem 274:12890-7
Waleh, N S; Calaoagan, J; Murphy, B J et al. (1998) The redox-sensitive human antioxidant responsive element induces gene expression under low oxygen conditions. Carcinogenesis 19:1333-7
Fenton, B M; Raubertas, R F; Boyce, D J (1995) Quantification of micro-regional heterogeneities in tumor oxygenation using intravascular HbO2 saturations. Radiat Res 141:49-56
Kiani, M F; Fenton, B M (1995) Inherent cellular differences may explain the dissimilar survival of RIF-1 and KHT tumour cells under aerobic and hypoxic conditions. Int J Radiat Biol 67:449-52
Waleh, N S; Brody, M D; Knapp, M A et al. (1995) Mapping of the vascular endothelial growth factor-producing hypoxic cells in multicellular tumor spheroids using a hypoxia-specific marker. Cancer Res 55:6222-6
Ausserer, W A; Bourrat-Floeck, B; Green, C J et al. (1994) Regulation of c-jun expression during hypoxic and low-glucose stress. Mol Cell Biol 14:5032-42
Mansbridge, J; Murphy, B; Morhenn, V et al. (1994) The response of human dermal microvascular endothelial cells to hypoxia. Biochim Biophys Acta 1223:209-18
Murphy, B J; Laderoute, K R; Chin, R J et al. (1994) Metallothionein IIA is up-regulated by hypoxia in human A431 squamous carcinoma cells. Cancer Res 54:5808-10
Kwok, T T; Sutherland, R M (1994) Repair of potentially lethal radiation damage in human squamous carcinoma cells after chronic hypoxia. Int J Radiat Oncol Biol Phys 29:255-8
Mansbridge, J N; Ausserer, W A; Knapp, M A et al. (1994) Adaptation of EGF receptor signal transduction to three-dimensional culture conditions: changes in surface receptor expression and protein tyrosine phosphorylation. J Cell Physiol 161:374-82

Showing the most recent 10 out of 58 publications