Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DE004660-21
Application #
2128990
Study Section
Special Emphasis Panel (NSS)
Project Start
1976-06-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Dentistry
Type
Schools of Dentistry
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Chatterjea, Sudeshna M; Resing, Katheryn A; Old, William et al. (2011) Optimization of filaggrin expression and processing in cultured rat keratinocytes. J Dermatol Sci 61:51-9
Pearton, D J; Nirunsuksiri, W; Rehemtulla, A et al. (2001) Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates. Exp Dermatol 10:193-203
Presland, R B; Tomic-Canic, M; Lewis, S P et al. (2001) Regulation of human profilaggrin promoter activity in cultured epithelial cells by retinoic acid and glucocorticoids. J Dermatol Sci 27:192-205
Presland, R B; Kimball, J R; Kautsky, M B et al. (1997) Evidence for specific proteolytic cleavage of the N-terminal domain of human profilaggrin during epidermal differentiation. J Invest Dermatol 108:170-8
Dale, B A; Presland, R B; Lewis, S P et al. (1997) Transient expression of epidermal filaggrin in cultured cells causes collapse of intermediate filament networks with alteration of cell shape and nuclear integrity. J Invest Dermatol 108:179-87
Presland, R B; Bassuk, J A; Kimball, J R et al. (1995) Characterization of two distinct calcium-binding sites in the amino-terminus of human profilaggrin. J Invest Dermatol 104:218-23
Nirunsuksiri, W; Presland, R B; Brumbaugh, S G et al. (1995) Decreased profilaggrin expression in ichthyosis vulgaris is a result of selectively impaired posttranscriptional control. J Biol Chem 270:871-6
Dale, B A; Kam, E (1993) Harlequin ichthyosis. Variability in expression and hypothesis for disease mechanism. Arch Dermatol 129:1471-7
Resing, K A; al-Alawi, N; Blomquist, C et al. (1993) Independent regulation of two cytoplasmic processing stages of the intermediate filament-associated protein filaggrin and role of Ca2+ in the second stage. J Biol Chem 268:25139-45
Kam, E; Resing, K A; Lim, S K et al. (1993) Identification of rat epidermal profilaggrin phosphatase as a member of the protein phosphatase 2A family. J Cell Sci 106 ( Pt 1):219-26

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