Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL031197-22
Application #
6927286
Study Section
Special Emphasis Panel (NSS)
Program Officer
Denholm, Elizabeth M
Project Start
1987-08-01
Project End
2007-07-31
Budget Start
2005-08-01
Budget End
2006-07-31
Support Year
22
Fiscal Year
2005
Total Cost
$398,750
Indirect Cost
Name
University of Alabama Birmingham
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Londino, James David; Lazrak, Ahmed; Noah, James W et al. (2015) Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infection. FASEB J 29:2712-25
Londino, James D; Lazrak, Ahmed; Jurkuvenaite, Asta et al. (2013) Influenza matrix protein 2 alters CFTR expression and function through its ion channel activity. Am J Physiol Lung Cell Mol Physiol 304:L582-92
Zhao, Run-Zhen; Nie, Hong-Guang; Su, Xue-Feng et al. (2012) Characterization of a novel splice variant of ? ENaC subunit in human lungs. Am J Physiol Lung Cell Mol Physiol 302:L1262-72
Collawn, James F; Matalon, Sadis (2012) The role of CFTR in transepithelial liquid transport in pig alveolar epithelia. Am J Physiol Lung Cell Mol Physiol 303:L489-91
Ji, Hong-Long; Zhao, Run-Zhen; Chen, Zai-Xing et al. (2012) ? ENaC: a novel divergent amiloride-inhibitable sodium channel. Am J Physiol Lung Cell Mol Physiol 303:L1013-26
Song, Weifeng; Wei, Shipeng; Zhou, Yongjian et al. (2010) Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines. J Biol Chem 285:9716-28
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Lazrak, Ahmed; Nita, Izabella; Subramaniyam, Devipriya et al. (2009) Alpha(1)-antitrypsin inhibits epithelial Na+ transport in vitro and in vivo. Am J Respir Cell Mol Biol 41:261-70
Ji, Hong-Long; Song, Weifeng; Gao, Zhiqian et al. (2009) SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms. Am J Physiol Lung Cell Mol Physiol 296:L372-83
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