Introduction: The Motivating Occupational Virtual Experiences In Therapy for kids (MOVE-IT) SBIR Phase I program will support intensive rehabilitation for pediatric hemiplegia through mixed-reality games that inspire high-dosage, task-directed upper extremity (UE) movements. Although dosage of training is almost uniformly associated with better outcomes in UE rehabilitation [1], [2], [3], [4], achieving the repetitions necessary to achieve lasting results through neuroplasticity is a formidable challenge. The MOVE-IT system will employ mixed-reality games that combine virtual- and real-world physical elements to provide therapists with a turn-key solution that engages patients in repetitive practice, facilitating evidence-based approaches including constraint- induced movement therapy (CIMT) and bimanual intensive therapy (BIM) [5]. This highly innovative solution employs modern video game engine technology, low-cost human motion tracking, and a robotic ?smart toy? to create games that promote adherence. Players are immersed in engaging storylines and multi-modal experiences that nourish the basic psychological needs underpinning human motivation. A web-based provider dashboard will enable therapists to track patient status, manage difficulty settings, as well as generate reports that document activity and progress via game-derived metrics that will be validated as part of the proposed Phase I activity. Problem to be addressed: Pediatric hemiplegia can result from Cerebral Palsy (CP) or acquired brain injury (including pediatric stroke, trauma, tumor, or other disease), and adversely affects motor functions essential to self-care, play, exploratory learning, and other daily activities [6]. CP, in particular, impacts more than 1 in 300 children in the U.S. [7], 60% of whom will experience some level of impairment in UE function [8]. Long-Term Goals: Provide a system for both clinical and home use that facilitates delivery of evidence-based therapies for hemiplegia, such as CIMT and BIM, while improving patient participation and adherence to these regimes. Reduce the cost of, and improve access to, state-of-the-art rehabilitation. Provide validated means for therapists to gauge and track patient progress in both clinical and home-based treatment programs. Phase I Summary: Barron Associates Inc. (award-winning innovators in video game therapy and advanced human-computer interfaces) has partnered with pediatric rehabilitation specialists at the University of Virginia (UVa) to create a highly innovative system that combines virtual world-based games with a robotic smart toy. The combination provides a mixed-reality experience that includes sight, sound, and touch. Phase I tasks include prototype development and demonstration of concept feasibility in testing with pediatric patients at the UVa Children?s Hospital. Commercial Opportunity: The MOVE-IT system will provide a low-cost, turn-key support tool for evidence- based, intensive therapies for use in rehabilitation in both clinics and home-based programs.

Public Health Relevance

MOVE-IT is a mixed-reality system that supports intensive upper extremity therapy for pediatric hemiplegia through fun and engaging game experiences. The proposed SBIR Phase I program addresses important public health concerns by: (1) making high-dosage rehabilitation programs more enjoyable and cost effective for patients; (2) supporting therapists in delivery of extended-duration, evidence-based programs; (3) improving access to remote and underserved areas by enabling home-based practice under parental supervision and remote guidance; and (4) providing validated metrics for use by therapists to guide, track, and document patient progress.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43HD092169-01A1
Application #
9555156
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Quatrano, Louis A
Project Start
2018-04-01
Project End
2019-03-31
Budget Start
2018-04-01
Budget End
2019-03-31
Support Year
1
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Barron Associates, Inc.
Department
Type
DUNS #
120839477
City
Charlottesville
State
VA
Country
United States
Zip Code
22901