The goal of this project is development of an ultrasonic imaging array capable of providing detailed images of the anterior segment of the eye. The array will be used to create anatomic images used for sizing of intraocular lens implants and treating pathological conditions, as well as pachymetric and topographic maps used in refractive surgery. During Phase I, we fabricated prototype transducer elements and demonstrated that the elements had sufficient sensitivity to detect the anterior and posterior corneal surfaces and Bowman's membrane in an ex vivo bovine eye. In Phase II, we plan to fabricate a complete two-dimensional imaging array and test the array on acoustic phantoms, rabbit eyes, and human eyes provided by the eye bank. Testing on animal and human eyes will be conducted by our clinical collaborators at the Weill Medical College of Cornell University. We will also work with our commercialization partner to integrate our array into their ocular imaging system.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44EY012320-02A1
Application #
6689104
Study Section
Special Emphasis Panel (ZRG1-BDCN-5 (10))
Program Officer
Helmsen, Ralph J
Project Start
1999-08-05
Project End
2005-08-31
Budget Start
2003-09-08
Budget End
2004-08-31
Support Year
2
Fiscal Year
2003
Total Cost
$465,424
Indirect Cost
Name
Creare, Inc.
Department
Type
DUNS #
072021041
City
Hanover
State
NH
Country
United States
Zip Code
03755