Population based studies have estimated the incidence of TBI but have not provided population-based estimates of subsequent disability. This population-based information is important for the appropriate planning and delivery of services to children disabled by TBI.? Objectives: (1) Determine the incidence of mild, moderate, and severe TBI in children and adolescents 0-18? years of age; (2) Determine the disability from different severities of TBI in children of different age groups;? (3) Determine how this disability changes over time after injury; (4) Identify risk and protective factors for? disability from TBI.? Study Design: In this project, we will conduct a population-based surveillance of children and adolescents? with TBI. From this surveillance, we will identify a sample of pediatric patients with TBI who will be recruited? and enrolled in the study. This sample will be stratified by severity and age to allow adequate numbers of? individuals at each severity level and each age group for study. Initial and base line measurements will be? obtained, and patients will be followed over time to determine outcomes from TBI.? Setting: Subjects will be identified in Emergency Departments, Hospitals and Medical Examiners in King? County, Washington, and Philadelphia County, Pennsylvania.? Participants: 1000 patients 0-18 years of age with mild, moderate or severe TBI.? Outcome Measures: We will examine patient and family disability pre-injury and at 3, 12, 24, and 36 months? post-TBl. This will include quality of life, social, emotional, behavioral and academic disability in patients and? family functioning and parenting stress.? Implications: This study will address many of these unanswered questions surrounding pediatric TBI. It will? provide population-based rates of the incidence and disability fromTBI, including mild, moderate and severe? based on medical record and interview data. It will follow patients and their families for three years after? injury, examining the degree to which recovery plateaus in the months following TBI. It will examine factors? which interact with the injury to produce disability, be they positive or negative influences on outcomes. The? study team represents an interdisciplinary group of very experienced investigators to carry out a rigorous? study to provide information to inform future research, care and policy.?

Agency
National Institute of Health (NIH)
Institute
National Center for Injury Prevention and Control (NCIPC)
Type
Injury Control Research and Demonstration Projects and Injury Prevention Research Centers (R49)
Project #
1R49CE001021-01
Application #
7183896
Study Section
National Center for Injury Prevention and Control Initial Review Group (SCE)
Program Officer
Blackman, Donald
Project Start
2006-09-01
Project End
2011-08-31
Budget Start
2006-09-01
Budget End
2007-08-31
Support Year
1
Fiscal Year
2006
Total Cost
$643,236
Indirect Cost
Name
University of Washington
Department
Pediatrics
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Jimenez, Nathalia; Symons, Rebecca G; Wang, Jin et al. (2016) Outpatient Rehabilitation for Medicaid-Insured Children Hospitalized With Traumatic Brain Injury. Pediatrics 137:
Jimenez, Nathalia; Osorio, Marisa; Ramos, Jessica L et al. (2015) Functional independence after inpatient rehabilitation for traumatic brain injury among minority children and adolescents. Arch Phys Med Rehabil 96:1255-61
Zonfrillo, Mark R; Durbin, Dennis R; Koepsell, Thomas D et al. (2014) Prevalence of and risk factors for poor functioning after isolated mild traumatic brain injury in children. J Neurotrauma 31:722-7
Jimenez, Nathalia; Ebel, Beth E; Wang, Jin et al. (2013) Disparities in disability after traumatic brain injury among Hispanic children and adolescents. Pediatrics 131:e1850-6
Tham, See Wan; Palermo, Tonya M; Wang, Jin et al. (2013) Persistent pain in adolescents following traumatic brain injury. J Pain 14:1242-9
Rivara, Frederick P; Koepsell, Thomas D; Wang, Jin et al. (2012) Incidence of disability among children 12 months after traumatic brain injury. Am J Public Health 102:2074-9
Rivara, Frederick P; Vavilala, Monica S; Durbin, Dennis et al. (2012) Persistence of disability 24 to 36 months after pediatric traumatic brain injury: a cohort study. J Neurotrauma 29:2499-504
Tham, See Wan; Palermo, Tonya M; Vavilala, Monica S et al. (2012) The longitudinal course, risk factors, and impact of sleep disturbances in children with traumatic brain injury. J Neurotrauma 29:154-61
Koepsell, Thomas D; Rivara, Frederick P; Vavilala, Monica S et al. (2011) Incidence and descriptive epidemiologic features of traumatic brain injury in King County, Washington. Pediatrics 128:946-54
Rivara, Frederick P; Koepsell, Thomas D; Wang, Jin et al. (2011) Disability 3, 12, and 24 months after traumatic brain injury among children and adolescents. Pediatrics 128:e1129-38

Showing the most recent 10 out of 11 publications