We are requesting funds to purchase a Typhoon model 9410 multi-mode flat bed scanner that will support the research programs of eight NIH-funded investigators at the University of Texas Medical School at Houston. The total estimated usage from these eight investigators is 80%, leaving an additional 20% of instrument time to other investigators at the Medical School. This state-of-the-art scanner has the capabilities of supporting chemiluminescent, phosphorimaging and multi-color fluorescence applications required to accomplish the Specific Aims of each investigator described in the application. No other instrument in the Medical School with the capabilities of the Typhoon 9410 scanner is available. The model 9410, as configured, will have three excitations sources providing four excitation wavelengths and dichroic/emission filter combinations capable of resolving up to seven emission wavelengths. These features will provide investigators with excellent flexibility in the choice of fluorescent probes for their specific analyses. In addition, the 9410 has scanning capabilities to 10
| Redell, John B; Moore, Anthony N; Grill, Raymond J et al. (2013) Analysis of functional pathways altered after mild traumatic brain injury. J Neurotrauma 30:752-64 |
