:
The specific aims of this proposal are to strengthen training for disparities research at Meharry, reinforce our disparities-related research programs in brain and behavior and infectious diseases, and to accelerate the transfer of disparities-related technologies into actual health care. Endowment earnings for disparities research training will be used to supplement predoctoral stipends, and to support student travel, a career symposium for postdoctoral fellows, seminars by visiting scientists, and an Office for Postdoctoral Training. Earnings earmarked for infectious diseases and brain and behavior will be used to supplement start-up funding for new faculty members, to sponsor seminars and travel to scientific meetings, and in other ways to help new faculty members move to independent status. In addition, earnings for brain and behavior will be used to support the start-up and development package for the newly-recruited Director of Meharry's Center for Brain and Behavior Research. Finally, earnings for technology transfer will be used to support nonpersonnel costs of technology transfer, including the cost of filing provisional patents, pursuing full patents, evaluating promising technologies, and deepening faculty members'and students'understanding of technology transfer by means of seminars and workshops.

Public Health Relevance

This proposal addresses three important issues in public health. First, aims to create a more diverse community of biomedical scientists that reflects the growing diversity of the American public. Second, it seeks to advance research in HIV, infectious diseases, and in brain and behavior;examples of the diseases that fall in these areas include, besides AIDS, tuberculosis, Alzheimer's disease, autism, and drug addiction. Third, it seeks to move discoveries that arise in biomedical laboratories to development and actual therapies more rapidly.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research and Institutional Resources Health Disparities Endowment Grants -Capacity Building (S21)
Project #
5S21MD000104-11
Application #
8120481
Study Section
Special Emphasis Panel (ZMD1-PA (R1))
Program Officer
Stinson, Nathaniel
Project Start
2001-09-30
Project End
2012-07-31
Budget Start
2011-08-01
Budget End
2012-07-31
Support Year
11
Fiscal Year
2011
Total Cost
$4,338,557
Indirect Cost
Name
Meharry Medical College
Department
Type
Schools of Medicine
DUNS #
041438185
City
Nashville
State
TN
Country
United States
Zip Code
37208
Cheatham, Amber M; Davis, Shamara E; Khatua, Atanu K et al. (2018) Blocking the 5' splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch. Sci Rep 8:8739
Dong, Xin-Hong; Ho, Meng-Hsuan; Liu, Bindong et al. (2018) Role of Porphyromonas gingivalis outer membrane vesicles in oral mucosal transmission of HIV. Sci Rep 8:8812
Suman, Shankar; Rachakonda, Girish; Mandape, Sammed N et al. (2018) Phospho-proteomic analysis of primary human colon epithelial cells during the early Trypanosoma cruzi infection phase. PLoS Negl Trop Dis 12:e0006792
Ignacio, Rosa Mistica C; Gibbs, Carla R; Lee, Eun-Sook et al. (2018) The TGF?-EGFR-Akt signaling axis plays a role in enhancing proinflammatory chemokines in triple-negative breast cancer cells. Oncotarget 9:29286-29303
Walker, Miriam Y; Pratap, Siddharth; Southerland, Janet H et al. (2018) Role of oral and gut microbiome in nitric oxide-mediated colon motility. Nitric Oxide 73:81-88
Shimamoto, Akiko; Rappeneau, Virginie (2017) Sex-dependent mental illnesses and mitochondria. Schizophr Res 187:38-46
Aronoff, David M; Correa, Hernan; Rogers, Lisa M et al. (2017) Placental pericytes and cytomegalovirus infectivity: Implications for HCMV placental pathology and congenital disease. Am J Reprod Immunol 78:
Williams, Amanda D; Korolkova, Olga Y; Sakwe, Amos M et al. (2017) Human alpha defensin 5 is a candidate biomarker to delineate inflammatory bowel disease. PLoS One 12:e0179710
Ho, Meng-Hsuan; Lamont, Richard J; Xie, Hua (2017) A novel peptidic inhibitor derived from Streptococcus cristatus ArcA attenuates virulence potential of Porphyromonas gingivalis. Sci Rep 7:16217
Ho, Meng-Hsuan; Lamont, Richard J; Xie, Hua (2017) Identification of Streptococcus cristatus peptides that repress expression of virulence genes in Porphyromonas gingivalis. Sci Rep 7:1413

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