EXCEED THE SPACE PROVIDED. This application is a request for continued support for a predoctoral and postdoctoral Multidisciplinary Parasitology and Vector Biology Training Program at Yale University. Yale University historically has had a major commitment to the study of parasitology. Currently the university has an integrated multidisciplinary program in parasitology and vector biology involving research laboratories within the Graduate and Medical Schools [Epidemiology & Public Health, Microbial Pathogenesis, Medicine, Genetics, Pharmacology, Ecology and Evolutionary Biology, Molecular Biophysics and Biochemistry]. The program has continued to grow over the past 5 years, with new faculty (Drs. Zheng, Fish, Iwasaki, Cappello, Baserga, Anderson and SOU) now participating in the program. The faculty have a history of working together collaboratively in research and teaching and serve together on student thesis and advisory committees. The research interests of the participating faculty span the broad spectrum of expertise and approaches [immunology, cell biology, molecular biology, entomology, biology and epidemiology] employed in the study of parasitology. Thus, the Trainees of this program have access to facilities and programs at Yale University acrossthe spectrum of disciplines relevant to parasitology. The predoctoral program includes: formal course work (concentrated in the first 2 years) to provide a solid grounding and breadth in the chosen area of research interest; laboratory rotations (first year) provide experience and familiarity with the multiple research environments available; selection by the student of a research advisor in the second year; preparation and defense of a research proposal as part of the qualifying examination (end of 2nd year). After the appointment of a thesis committee, the student prepares a research prospectus and progresses through her/his thesis research which finally results in the preparation of a thesis dissertation. Research (which spans the breadth of modern parasitology and vector biology) is the major component of both the predoctoral and postdoctoral programs. Trainees [predoctoral and postdoctoral], in addition to having access to the various facilities at Yale University, participate in several seminar and journal clubs focused on topics relevant to parasitology and vector biology. Further, trainees participate and present their research as part of a formalresearch- in-progress seminar series. Former trainees in the program have gone on to postdoctoral work (in the case of predoctoral trainees) and to positions as faculty in medical schools, universities, colleges or research staff in scientific research institutes and medically related industry. PERFORMANCE SITE ========================================Section End===========================================
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