This T32 Post-Doctoral training program has been funded by NIAID since July, 1994. The faculty members are from three neighboring institutes: University of California, San Diego (UCSD), and the La Jolla Institute for Allergy and Immunology (LIAI), which are both housed on the UCSD campus, and The Scripps Research Institute (TSRI) which is next door to UCSD. The trainees will have opportunities to be exposed to a wide range of allergy research topics. In addition, the inter-institutional training program serves as a catalyst for promoting interactions and collaborations among researchers from different institutes. All faculty members have well established research programs;their research backgrounds are diverse and when taken together encompass allergy, immunology, genetics, biochemistry, cell biology, signal transduction, glycobiology, and molecular biology. Therefore, this training program represents an interdisciplinary approach. The trainees can be involved in the following research areas: 1) regulation of IgE production, including Th1/Th2 differentiation;2) biology of inflammatory cells, including mast cells and eosinophils;3) biology of T cells;4) cell receptors critically involved in allergic reactions;5) signal transduction;6) inflammatory mediators/cytokines;7) functions of epithelial cells;and 7) adhesion. The goals of the program are 1) to provide trainees with a basic understanding of pathogenesis of allergic diseases;and 2) to foster the development of trainee's investigative skills, in particular, applying molecular and cellular biological approaches to study mechanisms of diseases. The program is open to MD's and Ph.D.'s interested in disease-oriented problems and committed to a career in basic research in clinical sciences. The trainee's are expected to devote full time to research, and training will be supplemented by conferences, seminars, journal clubs and courses. It can be expected that trainees will develop a solid background in the pathogenesis of allergic diseases and molecular and cellular mechanisms of allergic inflammation and become qualified and confident in embarking upon their careers as independent investigators in allergy research. The broad expertise and experience the trainees acquire will prepare them for independent research in biomedicine.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-GSM-I (M1))
Program Officer
Prograis, Lawrence J
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California San Diego
Internal Medicine/Medicine
Schools of Medicine
La Jolla
United States
Zip Code
Bhatia, Prerana; Chen, Meng; Christiansen, Sandra (2018) Marijuana and stoned fruit. Ann Allergy Asthma Immunol 120:536-537
Karta, Maya R; Rosenthal, Peter S; Beppu, Andrew et al. (2018) ?2 integrins rather than ?1 integrins mediate Alternaria-induced group 2 innate lymphoid cell trafficking to the lung. J Allergy Clin Immunol 141:329-338.e12
Chen, Meng; Kim, Alexander; Zuraw, Bruce et al. (2018) Mast cell disorders: Protean manifestations and treatment responses. Ann Allergy Asthma Immunol 121:128-130
PiƱa, Francisco; Yagisawa, Fumi; Obara, Keisuke et al. (2018) Sphingolipids activate the endoplasmic reticulum stress surveillance pathway. J Cell Biol 217:495-505
Miller, Marina; Vuong, Christine; Garcia, Meghan Farrell et al. (2018) Does reduced zona pellucida binding protein 2 (ZPBP2) expression on chromosome 17q21 protect against asthma? J Allergy Clin Immunol 142:706-709.e4
Chen, Meng; Riedl, Marc A (2017) Emerging Therapies in Hereditary Angioedema. Immunol Allergy Clin North Am 37:585-595
Miller, Marina; Tam, Arvin B; Mueller, James L et al. (2017) Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. J Immunol 198:3017-3022
Geng, Bob; Eastman, Jacqueline J; Mori, Karen et al. (2017) Utility of minor determinants for skin testing in inpatient penicillin allergy evaluation. Ann Allergy Asthma Immunol 119:258-261
Chen, Meng; Land, Michael (2017) Baked milk and baked egg oral immunotherapy. Immunotherapy 9:1201-1204
Song, Dae Jin; Miller, Marina; Beppu, Andrew et al. (2017) Rhinovirus Infection of ORMDL3 Transgenic Mice Is Associated with Reduced Rhinovirus Viral Load and Airway Inflammation. J Immunol 199:2215-2224

Showing the most recent 10 out of 58 publications