The objective of this program is to provide high quality training at the predoctoral and postdoctoral levels to prepare a select group of individuals for careers as independent investigators in microbial pathogenesis. The program is based in the Graduate Division of Biological and Biomedical Sciences at Emory University. It includes faculty members with primary appointments in four (4) Departments of the Emory University School of Medicine and Emory University College of Arts and Sciences and at the Centers for Disease Control and Prevention (CDC). The predoctoral program is research oriented with the major course requirements of an introductory core including biochemistry, prokaryotic genetics, virology and immunology. Research opportunities are provided in twenty-six (26) laboratories with active research programs in a range of important topics in microbial pathogenesis. Predoctoral trainees completing this program are well prepared to obtain postdoctoral training in excellent laboratories and to begin their careers as independent investigators, as is demonstrated by the success of our past trainees. Postdoctoral trainees will be well prepared to continue their careers as independent investigators. A short term training program will introduce medical students and undergraduates to research. We anticipate that the availability of this training of undergraduates will enable us to recruit interested minority candidates to our graduate research program. The unique aspects of our program include the availability of training in biodefense and in tuberculosis pathogenesis and the opportunities to work with faculty at the CDC and in basic science departments, the Department of Pathology and the Division of Infectious Diseases in the Department of Medicine at Emory University, either separately or in joint collaborative projects. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007470-13
Application #
7463783
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Mcsweegan, Edward
Project Start
1995-07-15
Project End
2011-06-30
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
13
Fiscal Year
2008
Total Cost
$354,008
Indirect Cost
Name
Emory University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Kraft, Colleen S; Basu, Debby; Hawkins, Paulina A et al. (2012) Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses. Retrovirology 9:22
Velazquez, Victoria M; Hon, Huiming; Ibegbu, Chris et al. (2012) Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection. Hepatology 56:2071-81
Basu, Debby; Kraft, Colleen S; Murphy, Megan K et al. (2012) HIV-1 subtype C superinfected individuals mount low autologous neutralizing antibody responses prior to intrasubtype superinfection. Retrovirology 9:76
Vachon, Virginia K; Conn, Graeme L (2012) Plasmid template design and in vitro transcription of short RNAs within a ""structure cassette"" for structure probing experiments. Methods Mol Biol 941:157-69
Shafer, William M; Ohneck, Elizabeth A (2011) Taking the gonococcus-human relationship to a whole new level: implications for the coevolution of microbes and humans. MBio 2:e00067-11
Ohneck, Elizabeth A; Zalucki, Yaramah M; Johnson, Paul J T et al. (2011) A novel mechanism of high-level, broad-spectrum antibiotic resistance caused by a single base pair change in Neisseria gonorrhoeae. MBio 2:
Brindley, Melinda A; Plemper, Richard K (2010) Blue native PAGE and biomolecular complementation reveal a tetrameric or higher-order oligomer organization of the physiological measles virus attachment protein H. J Virol 84:12174-84
Paal, Tanja; Brindley, Melinda A; St Clair, Courtney et al. (2009) Probing the spatial organization of measles virus fusion complexes. J Virol 83:10480-93
Churchward, Gordon; Bates, Christopher; Gusa, Asiya A et al. (2009) Regulation of streptokinase expression by CovR/S in Streptococcus pyogenes: CovR acts through a single high-affinity binding site. Microbiology 155:566-75
Leday, Temekka V; Gold, Kathryn M; Kinkel, Traci L et al. (2008) TrxR, a new CovR-repressed response regulator that activates the Mga virulence regulon in group A Streptococcus. Infect Immun 76:4659-68

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