The Biodefense Research Training and Career Development Program is a new initiative of the University of Virginia, which is in response to the NIAID Blue Ribbon Panel on Bioterrorism and Its Implications for Biomedical Research. The program goal is to provide a rich interdisciplinary experience to prepare pre- and postdoctoral students for careers in biodefense. Research themes encompass the biology of and host response to microbes, vaccines, therapeutics and diagnostic technologies for infections by potential agents of bioterrorism. The training of predoctoral students, M.D., and Ph.D. postdoctoral fellows is enriched by special activities of the program, including a new graduate course in biodefense, an expanded two semester course in molecular mechanisms of microbial pathogenesis, advanced immunology courses and colloquia, a research-in-progress series and a journal club. The program is comprised of 31 faculty from eight departments and two research centers within a five minute walk to the School of Medicine. All of our faculty collaborate, and 46% have co-published papers in the last five years.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZAI1-YL-M (M1))
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Garges, Susan
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University of Virginia
Internal Medicine/Medicine
Schools of Medicine
United States
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Steiner, Kevin L; Ahmed, Shahnawaz; Gilchrist, Carol A et al. (2018) Species of Cryptosporidia Causing Subclinical Infection Associated With Growth Faltering in Rural and Urban Bangladesh: A Birth Cohort Study. Clin Infect Dis 67:1347-1355
Moreau, G Brett; Qin, Aiping; Mann, Barbara J (2018) Zinc Acquisition Mechanisms Differ between Environmental and Virulent Francisella Species. J Bacteriol 200:
Sauder, Amber B; Kendall, Melissa M (2018) After the Fact(or): Posttranscriptional Gene Regulation in Enterohemorrhagic Escherichia coli O157:H7. J Bacteriol 200:
Gilchrist, Carol A; Cotton, James A; Burkey, Cecelia et al. (2018) Genetic Diversity of Cryptosporidium hominis in a Bangladeshi Community as Revealed by Whole-Genome Sequencing. J Infect Dis 218:259-264
Margulieux, Katie R; Liebov, Benjamin K; Tirumala, Venkata S K K S et al. (2017) Bacillus anthracis Peptidoglycan Integrity Is Disrupted by the Chemokine CXCL10 through the FtsE/X Complex. Front Microbiol 8:740
Mathers, Amy J; Stoesser, Nicole; Chai, Weidong et al. (2017) Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, blaKPC, in Klebsiella Species Is Elusive but Not Rare. Antimicrob Agents Chemother 61:
Gilmartin, Allissia A; Petri Jr, William A (2017) Exploring the mechanism of amebic trogocytosis: the role of amebic lysosomes. Microb Cell 5:1-3
Gilmartin, Allissia A; Ralston, Katherine S; Petri Jr, William A (2017) Inhibition of Amebic Lysosomal Acidification Blocks Amebic Trogocytosis and Cell Killing. MBio 8:
Luzader, Deborah H; Willsey, Graham G; Wargo, Matthew J et al. (2016) The Type Three Secretion System 2-Encoded Regulator EtrB Modulates Enterohemorrhagic Escherichia coli Virulence Gene Expression. Infect Immun 84:2555-65
Korpe, Poonum S; Haque, Rashidul; Gilchrist, Carol et al. (2016) Natural History of Cryptosporidiosis in a Longitudinal Study of Slum-Dwelling Bangladeshi Children: Association with Severe Malnutrition. PLoS Negl Trop Dis 10:e0004564

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