This Chemosensory Training Program (CTP), operating within the interdisciplinary Program in Neuroscience at Florida State University, is a continuing application in its 20th year. The CTP Program is geared to train the next generation of researchers to become leaders in basic neural mechanisms of chemosensory systems interfaced with behavior. The program is designed to prepare 4 pre- and 2 post-doctoral trainees for research careers focused on olfactory and gustatory senses in context. One important context is the regulation of food intake and metabolic state, dysregulation of which can lead to obesity and diabetes, or anorexia. The powerful links between chemosensory systems and brain circuitry associated with emotional, motivational, and neuromodulatory processes requires a wide perspective for full understanding. The broad long-term objective is to provide the basic neuroscience platform upon which clinical understanding of chemosensory disease is built using a wide spectrum of experimental approaches including molecular neurobiology, neurophysiology, biophysics, psychophysics, behavioral analysis, and computer applications. The strength of the CTP program that anticipates to provide 2 and 4 years of training for approximately five post- and fifteen pre- doctoral scholars, respectively, is the clos guidance of trainees by expert faculty whom are accustomed to productive collaborations fostered from a wealth of historical chemosensory knowledge that shapes cutting-edge investigations for training. Trainees have access to state- of-the-art custom-designed chemosensory equipment, technical support staff, and use of new building infrastructure to perform their research. Value-added activities of the training include - 1) chemosensory tutorials (readings and practicum), 2) evening gatherings (presentations, webinars, and informal and mentor/mentee career development), 3) structured oral, written, and analysis skill building and feedback, 4) depth of a continually evolving curriculum, and 5) an opportunity for alumni and speaker interaction that relays latest discoveries, allows career networking, and provides supplementary evaluation of the training program. Seven trainers will shape the intellectual and scientific practice of trainees at two levels as they bridge to independent and externally-funded scientific research programs in chemosensory problems important for the quality of life and human health.

Public Health Relevance

The Chemosensory Training Program at FSU affords pre-and post-doctoral trainees with unusually broad and deep opportunities to explore and master many research approaches to important questions about taste and smell function, whose loss involves devastating quality of life and whose central brain circuits are important in obesity, eating disorders, hypertension and other neurological disorders.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Institutional National Research Service Award (T32)
Project #
2T32DC000044-21
Application #
8854218
Study Section
Special Emphasis Panel (ZDC1)
Program Officer
Rivera-Rentas, Alberto L
Project Start
1995-07-01
Project End
2020-06-30
Budget Start
2015-07-01
Budget End
2016-06-30
Support Year
21
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Florida State University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
790877419
City
Tallahassee
State
FL
Country
United States
Zip Code
32306
Blakemore, Laura J; Corthell, John T; Trombley, Paul Q (2018) Kainate Receptors Play a Role in Modulating Synaptic Transmission in the Olfactory Bulb. Neuroscience 391:25-49
Macatee, Richard J; Albanese, Brian J; Clancy, Kevin et al. (2018) Distress intolerance modulation of neurophysiological markers of cognitive control during a complex go/no-go task. J Abnorm Psychol 127:12-29
Fardone, Erminia; Celen, Arda B; Schreiter, Nicholas A et al. (2018) Loss of odor-induced c-Fos expression of juxtaglomerular activity following maintenance of mice on fatty diets. J Bioenerg Biomembr :
Short, Nicole A; Boffa, Joseph W; Clancy, Kevin et al. (2018) Effects of emotion regulation strategy use in response to stressors on PTSD symptoms: An ecological momentary assessment study. J Affect Disord 230:77-83
Korshunov, Kirill S; Blakemore, Laura J; Trombley, Paul Q (2017) Dopamine: A Modulator of Circadian Rhythms in the Central Nervous System. Front Cell Neurosci 11:91
Schwartz, Austin B; Kapur, Anshika; Wang, Wentao et al. (2017) Margatoxin-bound quantum dots as a novel inhibitor of the voltage-gated ion channel Kv1.3. J Neurochem 140:404-420
Clancy, Kevin; Ding, Mingzhou; Bernat, Edward et al. (2017) Restless 'rest': intrinsic sensory hyperactivity and disinhibition in post-traumatic stress disorder. Brain 140:2041-2050
Bell, Genevieve A; Fadool, Debra Ann (2017) Awake, long-term intranasal insulin treatment does not affect object memory, odor discrimination, or reversal learning in mice. Physiol Behav 174:104-113
Westberry, Jenne M; Meredith, Michael (2017) Characteristic Response to Chemosensory Signals in GABAergic Cells of Medial Amygdala Is Not Driven by Main Olfactory Input. Chem Senses 42:13-24
McCarthy, Deirdre M; Bell, Genevieve A; Cannon, Elisa N et al. (2016) Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model. Dev Neurosci 38:354-364

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