This multi-disciplinary Medical Scientist Training Program (MSTP) is designed to provide education for trainees in clinical medicine and biomedical science and has as its goal the training of physician-scientists who, because of their simultaneous and rigorous education, are well-equipped biomedical investigators. The University of California, San Diego (UCSD) is a campus has considerable strength in the biomedical sciences, which is enhanced by the local community and nearby institutions. The strong ties between the School of Medicine (SOM), the adjoining UCSD General Campus and nearby research institutes (e.g., Salk Institute for Biological Studies [Salk], the Scripps Research Institute [TSRI], the Burnham Institute), as well as within the San Diego biomedical community create an academic environment highly suited for this MSTP and for the interdigitation of basic science, biomedical research and medical practice. The education is integrated: in the first two years, trainees take the preclinical SOM curriculum and utilize elective time to explore research opportunities and fulfill academic requirements in Graduate Programs. Students choose a Graduate Program toward the end of the preclinical curriculum. The site of research training depends upon the research area chosen by the student. Graduate training Programs that lead to the PhD degree include Anthropology, Biology, Biomedical Sciences, Bioengineering, Bioinformatics, Biophysics, Chemistry/ Biochemistry, Epidemiology, Neuroscience, Physics, and the TSRI Program in Chemical and Biological Sciences. In recent years most students have chosen the Biomedical Sciences or Neuroscience Graduate Program for their PhD training. Completion of clinical clerkships in the SOM leads to the M.D. degree. Flexibility of curriculum design is stressed and each student's program is individualized. In addition, the MSTP engages in a number of activities designed to enhance combined degree training and a sense of community among trainees embarking on careers as physician scientists. Evidence of the success of this MSTP is indicated by its high percentage of graduates who enter academic medicine and have careers as physician-scientists.

Public Health Relevance

The caliber of students is excellent, with graduates from leading universities throughout the US. Almost all of our graduates since 1990 have continued to pursue research, most in academic positions. This MSTP has grown through expanded research opportunities at UCSD and affiliated institutions, by a growing pool of high quality applicants and faculty and through support from UCSD, Salk and TSRI.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM007198-38S1
Application #
8496593
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter C
Project Start
1975-07-01
Project End
2015-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
38
Fiscal Year
2012
Total Cost
$48,582
Indirect Cost
$2,123
Name
University of California San Diego
Department
Pharmacology
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Chen, Meifan; Geoffroy, Cédric G; Meves, Jessica M et al. (2018) Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS. Cell Rep 22:3587-3597
Kang, Wendy; Tawhai, Merryn H; Clark, Alys R et al. (2018) In silico modeling of oxygen-enhanced MRI of specific ventilation. Physiol Rep 6:e13659
Geier, E T; Neuhart, I; Theilmann, R J et al. (2018) Spatial persistence of reduced specific ventilation following methacholine challenge in the healthy human lung. J Appl Physiol (1985) 124:1222-1232
Syed, Ismail; Lee, Jennifer; Moraes-Vieira, Pedro M et al. (2018) Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metab 27:419-427.e4
Meves, Jessica M; Geoffroy, Cédric G; Kim, Noah D et al. (2018) Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury. Exp Neurol 309:32-43
Geier, Eric T; Kubo, Kent; Theilmann, Rebecca J et al. (2018) The spatial pattern of methacholine bronchoconstriction recurs when supine, independently of posture during provocation, but does not recur between postures. J Appl Physiol (1985) :
Muse, Evan D; Yu, Shan; Edillor, Chantle R et al. (2018) Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. Proc Natl Acad Sci U S A 115:E4680-E4689
Vadodaria, Krishna C; Amatya, Debha N; Marchetto, Maria C et al. (2018) Modeling psychiatric disorders using patient stem cell-derived neurons: a way forward. Genome Med 10:1
Zapol, Warren M; Charles, H Cecil; Martin, Andrew R et al. (2018) Pulmonary Delivery of Therapeutic and Diagnostic Gases. J Aerosol Med Pulm Drug Deliv 31:78-87
Protopsaltis, Nicholas J; Chen, Allison J; Hwang, Vicky et al. (2018) Success in Attaining Independent Funding Among National Institutes of Health K Grant Awardees in Ophthalmology: An Extended Follow-up. JAMA Ophthalmol :

Showing the most recent 10 out of 306 publications