The Graduate Program in Biochemistry, Cellular and Molecular Biology (BCMB) is an interdisciplinary training program comprised of 93 faculty members in the Departments of Biological Chemistry, Molecular Biology and Genetics, Biophysics and Biophysical Chemistry, Pharmacology and Molecular Sciences, Cell Biology and Anatomy, Physiology and Neuroscience. The program trains young scientists in these disciplines and provides them with a breadth of knowledge and understanding so that they can initiate independent and fruitful research careers. Applicants apply to a single admissions committee and follow a single curriculum. They take five """"""""core"""""""" courses: Molecular Biology, Physical Biochemistry, Genetics, Bio-organic Chemistry, and Biochemistry and Cell Biology. The students also participate in several small group discussion courses, carry out three rotations in different laboratories, and then choose a thesis advisor. During the subsequent years they take several electives and attend journal clubs and departmental seminars presented by visiting scientists. Upon completion of their training, the students present their thesis research in a public seminar. The entire training program takes between 4 and 6 years. The 23-year-old program has been very successful. It continues to recruit high quality applicants. The successful candidates are outstanding science majors from top-ranked undergraduate schools. The """"""""steady-state"""""""" level of predoctoral students is 170, with an average of approximately 25 new students admitted each year. The graduates of the program hold research and teaching positions at all levels in academia, the government and industry. The training facilities are the classrooms and laboratories of the seven participating departments. The program fosters an extraordinary level of collaboration and interaction among the faculty. The students are an essential part of the scientific community and they appreciate not only the enormous variety of exciting research opportunities, but also the fact that the Johns Hopkins University School of Medicine is a very pleasant place to work.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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National Institute of General Medical Sciences Initial Review Group (BRT)
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Zatz, Marion M
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Johns Hopkins University
Schools of Medicine
United States
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Oldach, Laurel M; Gorshkov, Kirill; Mills 4th, William T et al. (2018) A biosensor for MAPK-dependent Lin28 signaling. Mol Biol Cell 29:1157-1167
Nakamura, Hideki; Lee, Albert A; Afshar, Ali Sobhi et al. (2018) Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions. Nat Mater 17:79-89
Sanders, Sara; Bartee, David; Harrison, Mackenzie J et al. (2018) Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors. PLoS One 13:e0197638
Little, Hannah C; Tan, Stefanie Y; Cali, Francesca M et al. (2018) Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle. Mol Cell Proteomics 17:1546-1563
Cairns, Leah; Tran, Thao; Fowl, Brendan H et al. (2018) Salvador has an extended SARAH domain that mediates binding to Hippo kinase. J Biol Chem 293:5532-5543
Kalin, Jay H; Wu, Muzhou; Gomez, Andrea V et al. (2018) Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nat Commun 9:53
Wang, Shuyan; Shi, Xiaohai; Wei, Shuang et al. (2018) Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells. J Biol Chem 293:6544-6555
Schuller, Anthony P; Zinshteyn, Boris; Enam, Syed Usman et al. (2018) Directed hydroxyl radical probing reveals Upf1 binding to the 80S ribosomal E site rRNA at the L1 stalk. Nucleic Acids Res 46:2060-2073
Lariviere, Patrick J; Szwedziak, Piotr; Mahone, Christopher R et al. (2018) FzlA, an essential regulator of FtsZ filament curvature, controls constriction rate during Caulobacter division. Mol Microbiol 107:180-197
Levine, Michelle S; Holland, Andrew J (2018) The impact of mitotic errors on cell proliferation and tumorigenesis. Genes Dev 32:620-638

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