The goal of this program is to provide postdoctoral fellows with research training enabling them to develop independent investigative careers devoted to improving care of the anesthetized/critically ill patient by advancing scientific knowledge in the field. The Department of Anesthesiology at Duke University Medical Center has intensively invested its resources in the development of multidisciplinary laboratory and clinical research environments to offer state-of-the-art research training experiences. We have also innovated in anesthesiology residency training to provide a research continuum that provides a highly effective preparatory phase prior to T32 enrollment. This proposal outlines the credentials of a distinguished training faculty who are willing and prepared to meet our goal. The training program involves a 2-3 year continuum when the trainees work under the close and direct supervision of a program faculty member on research projects of mutual interest. Emphasis is placed on learning responsible research skills, achieving mastery of the literature, independent hypothesis generation, experimental design, data analysis, presentation of research findings and competition for extramural funding. The trainees are encouraged to exploit relationships established with members of the program faculty for both enrichment of research skill repertoires and development of long-term collaborative relationships. The program is directed by the Program Director and a Research Council consisting of 6 senior scientists and the departmental chair. Trainees formally report to the program leadership at quarterly intervals to allow assessment of trainee performance and progress in achieving program goals. Trainees are sought from a national pool of eligible candidates with emphasis placed on recruitment of under-represented minority trainees. The primary focus of this program is the research training of select post-doctoral fellows. However, the program also is the cornerstone of our departmental research training endeavor setting high standards for investigative training offered to medical students, residents, junior faculty, and visiting scholars who participate in the research training process.

Public Health Relevance

This program is designed to provide intensive training in research relevant to patients requiring anesthesia and/or critical care. Provision of the next generation of physician-scientists will serv to improve medical care based on acquisition of scientific evidence and better understanding of relevant disease states

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008600-23
Application #
9486956
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Cole, Alison E
Project Start
1996-07-01
Project End
2021-06-30
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
23
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Duke University
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Andrew, Benjamin Y; Andrew, Elias Y; Cherry, Anne D et al. (2018) Intraoperative Renal Resistive Index as an Acute Kidney Injury Biomarker: Development and Validation of an Automated Analysis Algorithm. J Cardiothorac Vasc Anesth 32:2203-2209
Quinones, Quintin J; Levy, Jerrold H (2018) Ischemic Preconditioning and the Role of Antifibrinolytic Drugs: Translation From Bench to Bedside. Anesth Analg 126:384-386
Bottiger, Brandi A; Nicoara, Alina; Snyder, Laurie D et al. (2018) Frailty in the End-Stage Lung Disease or Heart Failure Patient: Implications for the Perioperative Transplant Clinician. J Cardiothorac Vasc Anesth :
George, Ronald B; McKeen, Dolores M; Dominguez, Jennifer E et al. (2018) A randomized trial of phenylephrine infusion versus bolus dosing for nausea and vomiting during Cesarean delivery in obese women. Can J Anaesth 65:254-262
Andrew, Benjamin Y; Cherry, Anne D; Hauck, Jennifer N et al. (2018) The Association of Aortic Valve Pathology With Renal Resistive Index as a Kidney Injury Biomarker. Ann Thorac Surg 106:107-114
Chen, Gang; Zhang, Yu-Qiu; Qadri, Yawar J et al. (2018) Microglia in Pain: Detrimental and Protective Roles in Pathogenesis and Resolution of Pain. Neuron 100:1292-1311
Chamessian, Alexander; Young, Michael; Qadri, Yawar et al. (2018) Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn. Sci Rep 8:6809
Levy, Jerrold H; Koster, Andreas; Quinones, Quintin J et al. (2018) Antifibrinolytic Therapy and Perioperative Considerations. Anesthesiology 128:657-670
Dominguez, Jennifer E; Street, Linda; Louis, Judette (2018) Management of Obstructive Sleep Apnea in Pregnancy. Obstet Gynecol Clin North Am 45:233-247
Allen, T K; Mishriky, B M; Klinger, R Y et al. (2018) The impact of neuraxial clonidine on postoperative analgesia and perioperative adverse effects in women having elective Caesarean section-a systematic review and meta-analysis. Br J Anaesth 120:228-240

Showing the most recent 10 out of 61 publications