The University of Maryland seeks new support for Ph.D. degree granting, umbrella program in Cell and Molecular Biology, based within a long-standing interdisciplinary training program in Molecular and Cell Biology (MOCB). This program takes advantage of the enormous pool of expertise in molecular and cell biology both on campus and in affiliated Institutions in the Washington, D.C. area, including the University of Maryland Biotechnology Institute, the National Institutes of Health and Children's Hospital. Major investments in the Biosciences by the State of Maryland, the leadership of the University, and the College of Chemical and Life Sciences have resulted in a huge expansion of basic sciences at UM. This ongoing growth period has resulted in a dramatic improvement in the quality of research and teaching in basic sciences on our campus. The expansion in the number of research-oriented, well-funded faculty has raised standards for student training and recruitment. Support is requested for 2 students in year one, 4 students in year 2, 5 students in year 3, and 6 students in years four and five. Students will enter a well-structured, highly mentored program that is run by the Program Director and a Steering Committee. Students complete a stringent core curriculum in the first year, while rotating through three laboratories. They then begin their Thesis work and complete a required class in Bioethics and 4 elective credits. An Advisory committee monitors student progress throughout their enrollment. The Qualifying exam consists of a Thesis proposal and oral defense. Students are expected to attend Seminars and journal clubs and to present their work at national and international scientific meetings and to publish in high quality journals. The MOCB program and all bioscience programs at UM will be enhanced by an NIH-sponsored training Program in Cell and Molecular Biology. This program will bolster efforts to continue to raise standards for training, by implementing new infrastructure and oversight, by forging more cohesive interactions with units off-campus, and by raising standards for recruitment, with particular focus on recruitment of underrepresented minorities. Graduates of our program will be well prepared to begin careers as independent scientists and contribute to society by advancing knowledge and promoting research. Our students will go on to jobs in academics, government agencies and industry and make major contributions to emerging areas of science and technology in our country.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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National Institute of General Medical Sciences Initial Review Group (BRT)
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Gindhart, Joseph G
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University of Maryland College Park
Schools of Earth Sciences/Natur
College Park
United States
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O'Neill, Natalie A; Eppler, Haleigh B; Jewell, Christopher M et al. (2018) Harnessing the lymph node microenvironment. Curr Opin Organ Transplant 23:73-82
Gosselin, Emily A; Eppler, Haleigh B; Bromberg, Jonathan S et al. (2018) Designing natural and synthetic immune tissues. Nat Mater 17:484-498
Nazario-Toole, Ashley E; Robalino, Javier; Okrah, Kwame et al. (2018) The Splicing Factor RNA-Binding Fox Protein 1 Mediates the Cellular Immune Response in Drosophila melanogaster. J Immunol 201:1154-1164
Joldersma, Dirk; Liu, Zhongchi (2018) The making of virgin fruit: the molecular and genetic basis of parthenocarpy. J Exp Bot 69:955-962
Gu, Chao; Zhou, Yu-Hang; Shu, Wei-Sheng et al. (2018) RNA-Seq analysis unveils gene regulation of fruit size cooperatively determined by velocity and duration of fruit swelling in peach. Physiol Plant 164:320-336
Joldersma, Dirk; Liu, Zhongchi (2018) Plant genetics enters the nano age? J Integr Plant Biol 60:446-447
Fischer, Matthew D; Mgboji, Emmanuel; Liu, Zhongchi (2018) Pyrite cloning: a single tube and programmed reaction cloning with restriction enzymes. Plant Methods 14:91
Le, My-Tra; Kasprzak, Wojciech K; Shapiro, Bruce A et al. (2017) Combined single molecule experimental and computational approaches for understanding the unfolding pathway of a viral translation enhancer that participates in a conformational switch. RNA Biol 14:1466-1472
Quigley, Jeff; Hughitt, V Keith; Velikovsky, Carlos A et al. (2017) The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis. MBio 8:
Le, My-Tra; Kasprzak, Wojciech K; Kim, Taejin et al. (2017) Folding behavior of a T-shaped, ribosome-binding translation enhancer implicated in a wide-spread conformational switch. Elife 6:

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