This proposal is a competitive renewal application for an Institutional National Research Service Award training grant that will continue a focus for training in the epidemiology and prevention of cardiovascular diseases at the University of Washington. We propose to continue to use the following training strategy: combine training through existing graduate degree programs in Epidemiology at an outstanding School of Public Health and Community Medicine with interdisciplinary research experiences in the epidemiology and prevention of cardiovascular disease. The Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, will provide the formal coursework and degree programs;and, the Cardiovascular Health Research Unit, Department of Medicine, School of Medicine, University of Washington will provide the research experience. The teaching and research activities of the faculty at the University of Washington who are active in cardiovascular research have continued to grow over the past four years and provide a variety of opportunities for formal training and research experiences related to the epidemiology and prevention of cardiovascular diseases including: cardiovascular epidemiology, genetic epidemiology, molecular/biochemical epidemiology, nutritional epidemiology, pharmacoepidemiology, infectious disease epidemiology, neuroepidemiology, environmental epidemiology, and preventive cardiology health services. The program will involve both pre-doctoral students (6 slots per year) who seek the Ph.D. in Epidemiology and post-doctoral students, physicians and other health professionals (2 slots per year), who seek the M.S. or M.P.H. degree in Epidemiology. The mix of trainees models the collaborative research teams that we have found enhance research productivity. The University of Washington Cardiovascular Epidemiology Training Program was initially funded by NHLBI in 1998 and competitively renewed in 2002. The program has attracted outstanding students to careers in cardiovascular epidemiology and prevention. To date, 7 post-doctoral and 6 pre-doctoral trainees have completed the program. The early success of these trainees is notable, as they continue to make important contributions to research on cardiovascular epidemiology and prevention. Currently, there are 2 post-doctoral and 6 pre-doctoral trainees in the Program. In short, the program continues to achieve its goal of increasing the numbers of professionals, both Ph.D. cardiovascular epidemiologists and physician-epidemiologists, with the knowledge and skills to develop, implement, evaluate, translate, and disseminate research in the epidemiology and prevention of cardiovascular diseases.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Silsbee, Lorraine M
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Washington
Public Health & Prev Medicine
Schools of Public Health
United States
Zip Code
Harrington, L B; Blondon, M; Cushman, M et al. (2018) Vasomotor symptoms and the risk of incident venous thrombosis in postmenopausal women. J Thromb Haemost 16:886-892
Harrington, L B; Marck, B T; Wiggins, K L et al. (2017) Cross-sectional association of endogenous steroid hormone, sex hormone-binding globulin, and precursor steroid levels with hemostatic factor levels in postmenopausal women. J Thromb Haemost 15:80-90
Wallace, E R; Siscovick, D S; Sitlani, C M et al. (2017) Incident atrial fibrillation and the risk of fracture in the cardiovascular health study. Osteoporos Int 28:719-725
Ehlert, Alexa N; Heckbert, Susan R; Wiggins, Kerri L et al. (2017) Administrative billing codes accurately identified occurrence of electrical cardioversion and ablation/maze procedures in a prospective cohort study of atrial fibrillation patients. Clin Cardiol 40:1227-1230
Harrington, Laura B; Blondon, Marc; Cushman, Mary et al. (2017) The cross-sectional association between vasomotor symptoms and hemostatic parameter levels in postmenopausal women. Menopause 24:360-370
Mohanty, April F; Siscovick, David S; Williams, Michelle A et al. (2016) Periconceptional seafood intake and pregnancy complications. Public Health Nutr 19:1795-803
Wallace, Erin R; Siscovick, David S; Sitlani, Colleen M et al. (2016) Incident Atrial Fibrillation and Disability-Free Survival in the Cardiovascular Health Study. J Am Geriatr Soc 64:838-43
Harrington, Laura B; Weiss, Noel S; Wiggins, Kerri L et al. (2016) Prior hysterectomy and oophorectomy and incident venous thrombosis risk among postmenopausal women: a population-based, case-control study. Menopause 23:143-9
Lawrence, Gabriella M; Siscovick, David S; Calderon-Margalit, Ronit et al. (2016) Cohort Profile: The Jerusalem Perinatal Family Follow-Up Study. Int J Epidemiol 45:343-52
Chi, Gloria C; Liu, Yongmei; MacDonald, James W et al. (2016) Long-term outdoor air pollution and DNA methylation in circulating monocytes: results from the Multi-Ethnic Study of Atherosclerosis (MESA). Environ Health 15:119

Showing the most recent 10 out of 80 publications