The primary goal of our training program in """"""""Cardiovascular Biomechanics and Imaging"""""""" is to attract, train, and graduate highly qualified, multi-disciplinary scientists in the area of cardiovascular bioengineering at pre- and post-doctoral levels. The program was created 5 years ago in response to: i) the dearth of training opportunities in Bioengineering available at the University of Colorado, and indeed within the greater Rocky Mountain area;and ii) the relative lack of cardiovascular bioengineering research efforts within the University of Colorado and the greater Rocky Mountain area. In responding to these two key needs, we believe the first 5 years of the program have been very successful. Key achievements during the first cycle include placement of all post-doctoral trainees and 3 out of 4 pre-doctoral trainees in academic research positions, successfully moving several trainees off this institutional grant and into individual fellowship awards, and significant expansion of bioengineering research and education and the University of Colorado. We believe that the combination of outstanding outcomes, significant institutional support, and growing reputation make a compelling argument to continue this program for the next 5 years and thereby establish the University of Colorado as a premiere training institution for cardiovascular bioengineering.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZHL1-CSR-M (F1))
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Carlson, Drew E
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University of Colorado at Boulder
Engineering (All Types)
Schools of Engineering
United States
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Schäfer, Michal; Kheyfets, Vitaly O; Barker, Alex J et al. (2018) Reduced shear stress and associated aortic deformation in the thoracic aorta of patients with chronic obstructive pulmonary disease. J Vasc Surg 68:246-253
Gates, Phillip E; Gurung, Arati; Mazzaro, Luciano et al. (2018) Measurement of Wall Shear Stress Exerted by Flowing Blood in the Human Carotid Artery: Ultrasound Doppler Velocimetry and Echo Particle Image Velocimetry. Ultrasound Med Biol 44:1392-1401
St Clair, Joshua R; Ramirez, David; Passman, Samantha et al. (2018) Contrast-enhanced ultrasound measurement of pancreatic blood flow dynamics predicts type 1 diabetes progression in preclinical models. Nat Commun 9:1742
Govindarajan, Tina; Shandas, Robin (2017) Shape Memory Polymers Containing Higher Acrylate Content Display Increased Endothelial Cell Attachment. Polymers (Basel) 9:
McClatchey, Penn M; Frisbee, Jefferson C; Reusch, Jane E B (2017) A conceptual framework for predicting and addressing the consequences of disease-related microvascular dysfunction. Microcirculation 24:
Gurung, Arati; Gates, Phillip E; Mazzaro, Luciano et al. (2017) Echo Particle Image Velocimetry for Estimation of Carotid Artery Wall Shear Stress: Repeatability, Reproducibility and Comparison with Phase-Contrast Magnetic Resonance Imaging. Ultrasound Med Biol 43:1618-1627
Mason McClatchey, P; Bauer, Timothy A; Regensteiner, Judith G et al. (2017) Dissociation of local and global skeletal muscle oxygen transport metrics in type 2 diabetes. J Diabetes Complications 31:1311-1317
Mason McClatchey, P; Wu, Fan; Olfert, I Mark et al. (2017) Impaired Tissue Oxygenation in Metabolic Syndrome Requires Increased Microvascular Perfusion Heterogeneity. J Cardiovasc Transl Res 10:69-81
McClatchey, P Mason; Keller, Amy C; Bouchard, Ron et al. (2016) Fully automated software for quantitative measurements of mitochondrial morphology. Mitochondrion 26:58-71
McClatchey, P Mason; Keller, Amy C; Bouchard, Ron et al. (2016) Raw and processed microscope images of fixed cells at baseline and following various experimental perturbations. Data Brief 6:998-1006

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