This is an application for continuing support for an institutional Training Program in neuropsychopharmacology. Support is requested for five postdoctoral and three predoctoral Fellows yearly. Postdoctoral Fellows in the Program will be either (1)students with doctoral degree in pharmacology, psychology, psychobiology or a related discipline, or (2) physicians who have completed at least three years of specialist training in psychiatry or, in selected instances, other specialty areas (e.g., pediatrics, neurology). Predoctoral fellows will be graduates of a four-year program in biology, chemistry, psychology or a related discipline; upon successful completion of the program, they will receive a doctoral degree in pharmacology or neuroscience. A multidisciplinary program has been developed involving faculty from six departments in the School of Medicine as well as faculty from the Schools of Veterinary Medicine and Arts and Sciences. The faculty members of the Program have a history of collaboration in both teaching and research projects.
The aim of the Program is not only to train scientists who will be able to carry out productive research in their individual fields but also to work effectively at the """"""""preclinical-clinical"""""""" interface. The objective is addressed by having the postdoctoral Fellows attend specific courses, by arranging for clinical exposure for all non-physicians and by developing interactions between preclinical and clinical investigators. The didactic portion of the Program comprises about 15% of a postdoctoral Fellow's time; most of their time is spent doing research in the facilities of one or more of the 30 faculty members of the Training Program. The approaches and expertise of the faculty are broad and diverse and enable us to provide training at the molecular, cellular, neuroanatomical, animal behavioral and/or clinical level. The predoctoral Fellows are advanced graduate students in pharmacology or neuroscience and take a series of courses designed to provide them with background in the anatomical, biochemical and physiological bases of pharmacology, with an emphasis on neuropsychopharmacology. Specific courses have been developed to meet these goals. Although a standard curriculum has been devised, the Training Program is structured so that it can be modified to fit the particular needs and career plans of each individual student. The goal of the Training Program is to supplement the research program of graduate student with activities (seminar presentations, colloquia) that emphasize the consideration of clinical practice in psychiatry in the conduct of basic research.
| Manners, M T; Yohn, N L; Lahens, N F et al. (2018) Transgenerational inheritance of chronic adolescent stress: Effects of stress response and the amygdala transcriptome. Genes Brain Behav :e12493 |
| Browne, Caroline A; Falcon, Edgardo; Robinson, Shivon A et al. (2018) Reversal of Stress-Induced Social Interaction Deficits by Buprenorphine. Int J Neuropsychopharmacol 21:164-174 |
| Crist, Richard C; Reiner, Benjamin C; Berrettini, Wade H (2018) A review of opioid addiction genetics. Curr Opin Psychol 27:31-35 |
| Reiner, David J; Mietlicki-Baase, Elizabeth G; Olivos, Diana R et al. (2017) Amylin Acts in the Lateral Dorsal Tegmental Nucleus to Regulate Energy Balance Through Gamma-Aminobutyric Acid Signaling. Biol Psychiatry 82:828-838 |
| Robinson, Shivon A; Erickson, Rebecca L; Browne, Caroline A et al. (2017) A role for the mu opioid receptor in the antidepressant effects of buprenorphine. Behav Brain Res 319:96-103 |
| Egbujo, Chijioke N; Sinclair, Duncan; Hahn, Chang-Gyu (2016) Dysregulations of Synaptic Vesicle Trafficking in Schizophrenia. Curr Psychiatry Rep 18:77 |
| Robinson, Shivon A; Brookshire, Bethany R; Lucki, Irwin (2016) Corticosterone exposure augments sensitivity to the behavioral and neuroplastic effects of fluoxetine in C57BL/6 mice. Neurobiol Stress 3:34-42 |
| Schmidt, Heath D; Mietlicki-Baase, Elizabeth G; Ige, Kelsey Y et al. (2016) Glucagon-Like Peptide-1 Receptor Activation in the Ventral Tegmental Area Decreases the Reinforcing Efficacy of Cocaine. Neuropsychopharmacology 41:1917-28 |
| Zitnik, Gerard A; Curtis, Andrè L; Wood, Susan K et al. (2016) Adolescent Social Stress Produces an Enduring Activation of the Rat Locus Coeruleus and Alters its Coherence with the Prefrontal Cortex. Neuropsychopharmacology 41:1376-85 |
| Reiner, David J; Mietlicki-Baase, Elizabeth G; McGrath, Lauren E et al. (2016) Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance. J Neurosci 36:3531-40 |
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