Continuing support is requested for a broadly-based, interdisciplinary training program that provides fundamental Pre-doctoral training in the neurosciences at the University of Cincinnati. The proposed training program will support students for the first two years of their graduate education. Trainees are recruited nationally and are selected on a competitive basis. The specific objectives of the training program include: 1) recruiting quality trainees showing outstanding potential for careers in neuroscience;2) delivering solid didactic training in basic neuroscience and the ethical conduct of research, 3) fostering state-of-the art neuroscience research experiences in top neuroscience laboratories, 4) creating an enriched neuroscience environment through journal clubs, seminars, attendance at local, national and international meetings, and numerous events and activities promoting program interaction and cohesion, and 5) preparing students for neuroscience careers through coursework in academic survival skills, career symposia and mentoring. The proposed training program is supported by a growing and vigorous neuroscience community. The University fosters the growth of neuroscience research through faculty recruitments and resource allocation, and supports the Neuroscience Graduate Program through an administrative budget and a limited amount of stipend and tuition support. Participating faculty have active and productive research programs incorporating a variety of approaches to study of the nervous system, spanning basic to translational neuroscience. As a result of this training grant, improvements in our applicant pool have resulted in a very productive and successful student body, as illustrated by the success of our trainees in obtaining quality post-doctoral positions, independent funding and faculty positions. New initiatives proposed for this funding period supplement our program by addition of new courses in neuroscience;implementation of new plans for general and minority recruitment;interaction with the new undergraduate neuroscience major;and public outreach. It is anticipated that our trainees will take an active role In shaping future discoveries of direct benefit to diagnosis, prevention and treatment of nervous system disease or pathology.

Public Health Relevance

;Neuroscience research is critical for discovering new cures and treatments for debilitating neurodegenerative, neurological and psychiatric disease. This proposal provides broad-based training to provide a next generation of scientist's education in the fundamentals of neuroscience and experience in state-of-the-art basic as well as translational neuroscience research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
2T32NS007453-11A2
Application #
7866988
Study Section
Special Emphasis Panel (ZNS1-SRB-P (54))
Program Officer
Korn, Stephen J
Project Start
1997-09-30
Project End
2015-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
11
Fiscal Year
2010
Total Cost
$119,538
Indirect Cost
Name
University of Cincinnati
Department
Psychiatry
Type
Schools of Medicine
DUNS #
041064767
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Schock, Elizabeth N; Struve, Jaime N; Chang, Ching-Fang et al. (2017) A tissue-specific role for intraflagellar transport genes during craniofacial development. PLoS One 12:e0174206
Smith, Brittany L; Lyons, Carey E; Correa, Fernanda Guilhaume et al. (2017) Behavioral and physiological consequences of enrichment loss in rats. Psychoneuroendocrinology 77:37-46
Snedeker, John; Schock, Elizabeth N; Struve, Jamie N et al. (2017) Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development. PLoS One 12:e0173258
Jensen, Victoria N; Romer, Shannon H; Turner, Sarah M et al. (2017) Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease. J Vis Exp :
Nguyen, Elizabeth T; Streicher, Joshua; Berman, Sarah et al. (2017) A mixed glucocorticoid/mineralocorticoid receptor modulator dampens endocrine and hippocampal stress responsivity in male rats. Physiol Behav 178:82-92
Hosford, Bethany E; Rowley, Shane; Liska, John P et al. (2017) Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression. Sci Rep 7:18015
Cassella, Sarah N; Hemmerle, Ann M; Lundgren, Kerstin H et al. (2016) Maternal immune activation alters glutamic acid decarboxylase-67 expression in the brains of adult rat offspring. Schizophr Res 171:195-9
Packard, Amy E B; Egan, Ann E; Ulrich-Lai, Yvonne M (2016) HPA Axis Interactions with Behavioral Systems. Compr Physiol 6:1897-1934
Herman, James P; McKlveen, Jessica M; Ghosal, Sriparna et al. (2016) Regulation of the Hypothalamic-Pituitary-Adrenocortical Stress Response. Compr Physiol 6:603-21
Smith, Brittany L; Schmeltzer, Sarah N; Packard, Benjamin A et al. (2016) Divergent effects of repeated restraint versus chronic variable stress on prefrontal cortical immune status after LPS injection. Brain Behav Immun 57:263-270

Showing the most recent 10 out of 29 publications