This is a competing continuation proposal for Years 23-28 of the Health and Retirement Study (HRS) cooperative agreement, in response to NIA RFA #AG-12-001. We propose to continue core data collection on the steady-state design laid out in the two previous renewal cycles, and collect biomarkers and measures of physical performance in in-person interviews on the rotating half-sample design established in the previous cycle. HRS provides a uniquely rich, nationally representative longitudinal dataset for the community of scientific and policy researchers who study the health, economics and demography of aging. It provides a research data base that can simultaneously support cross-sectional descriptions of the U.S. population over the age of fifty, longitudinal studies of a given cohort over a substantia period of time and research on cross-cohort trends. The HRS project creates a data system extending beyond the core survey data. One component of this extended data system consists of linkages to administrative data, including Social Security earnings and benefit records, Medicare utilization and diagnostic records, employer pension records, and the National Death Index. We plan to expand these linkages to include Medicaid records, links to Veteran's Administration data, and information on nursing home residents from the Minimum Data Set. Another component is genome-wide genotyping data from consenting respondents that will be available in dbGaP by the start of this next renewal cycle. The HRS provides public use data designed to allow the full power and creativity of America's scientific community to address the challenges of an aging population. The HRS is making a significant impact on research on aging through investigator-initiated research which uses the HRS as an input without charge to researchers or granting agencies. Over 1,000 peer-reviewed journal publications by over 1,000 different authors and co-authors and over 200 doctoral dissertations have appeared based on the HRS.

Public Health Relevance

The Health and Retirement Study is the nation's pre-eminent resource for publicly-available data on the economic well-being and physical and mental health of its older population. Its longitudinal design allows rigorous examination of causal pathways among social, psychological, economic, and health variables and the impact of policy changes on these relationships.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AG009740-25
Application #
8617784
Study Section
Special Emphasis Panel (ZAG1)
Program Officer
Patmios, Georgeanne E
Project Start
1998-01-01
Project End
2017-12-31
Budget Start
2014-05-01
Budget End
2014-12-31
Support Year
25
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Miscellaneous
Type
Organized Research Units
DUNS #
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Heger, Dörte; Korfhage, Thorben (2018) Care choices in Europe: To Each According to His or Her Needs? Inquiry 55:46958018780848
Davies, Gail; Lam, Max; Harris, Sarah E et al. (2018) Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nat Commun 9:2098
Hong, Ickpyo; Reistetter, Timothy A; Díaz-Venegas, Carlos et al. (2018) Cross-national health comparisons using the Rasch model: findings from the 2012 US Health and Retirement Study and the 2012 Mexican Health and Aging Study. Qual Life Res 27:2431-2441
Belsky, Daniel W; Domingue, Benjamin W; Wedow, Robbee et al. (2018) Genetic analysis of social-class mobility in five longitudinal studies. Proc Natl Acad Sci U S A 115:E7275-E7284
Zissimopoulos, Julie M; Tysinger, Bryan C; St Clair, Patricia A et al. (2018) The Impact of Changes in Population Health and Mortality on Future Prevalence of Alzheimer's Disease and Other Dementias in the United States. J Gerontol B Psychol Sci Soc Sci 73:S38-S47
Zhan, Yiqiang; Clements, Mark S; Roberts, Rosebud O et al. (2018) Association of telomere length with general cognitive trajectories: a meta-analysis of four prospective cohort studies. Neurobiol Aging 69:111-116
Wehby, George L; Domingue, Benjamin W; Wolinsky, Fredric D (2018) Genetic Risks for Chronic Conditions: Implications for Long-term Wellbeing. J Gerontol A Biol Sci Med Sci 73:477-483
Hoffman, Geoffrey J; Ha, Jinkyung; Alexander, Neil B et al. (2018) Underreporting of Fall Injuries of Older Adults: Implications for Wellness Visit Fall Risk Screening. J Am Geriatr Soc 66:1195-1200
Weden, Margaret M; Shih, Regina A; Kabeto, Mohammed U et al. (2018) Secular Trends in Dementia and Cognitive Impairment of U.S. Rural and Urban Older Adults. Am J Prev Med 54:164-172
McAninch, Elizabeth A; Rajan, Kumar B; Evans, Denis A et al. (2018) A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans. J Clin Endocrinol Metab 103:1818-1826

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