During the bridge-funding period, the SWAN CC will have three primary missions: 1. Maintain the Administrative Infrastructure for SWAN. The CC provides leadership and comprehensive support for all of the scientific committees and the administrative committees including the Steering Committee and the Publications and Presentations Committee. This committee structure is essential for the research productivity of SWAN. The CC also maintains the study website and communication systems (webinars and conference calls) for the investigators. 2. Finalize, Deliver and Support SWAN Datasets. The CC is completing the final phases of data cleaning, data calibration and documentation for SWAN V. These detailed analytic datasets are provided to all SWAN investigators and required for SWAN research and publications. Moreover, the CC will complete the creation of the de-identified SWAN V and longitudinal datasets for the NIA AgingResearchBiobank. The CC will provide support to internal and external investigators who are interested in accessing and analyzing the SWAN data. 3. Conduct Statistical Analyses and Produce Manuscripts. The CC will statistically analyze the SWAN data and collaborate with investigators to prepare manuscripts to fulfill the SWAN V aims and provide further insight on the science of women?s health, menopause and aging. Our expertise with the complex SWAN science and data is critical to the success of the study at large. 1

Public Health Relevance

SWAN will fill important gaps in understanding the impact of the menopausal transition and mid-life aging on women?s health and functioning in the postmenopausal years. Accordingly, it will provide useful information to guide clinical decisions in mid-life and beyond in women who have diverse life experiences and socioeconomic and racial/ethnic characteristics.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project--Cooperative Agreements (U01)
Project #
3U01AG012553-24S1
Application #
9967393
Study Section
Program Officer
Dutta, Chhanda
Project Start
1994-09-30
Project End
2020-06-30
Budget Start
2019-08-15
Budget End
2020-06-30
Support Year
24
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15260
Crawford, Sybil L; Crandall, Carolyn J; Derby, Carol A et al. (2018) Menopausal hormone therapy trends before versus after 2002: impact of the Women's Health Initiative Study Results. Menopause :
Karlamangla, Arun S; Burnett-Bowie, Sherri-Ann M; Crandall, Carolyn J (2018) Bone Health During the Menopause Transition and Beyond. Obstet Gynecol Clin North Am 45:695-708
Beatty Moody, Danielle L; Chang, Yuefang; Brown, Charlotte et al. (2018) Everyday Discrimination and Metabolic Syndrome Incidence in a Racially/Ethnically Diverse Sample: Study of Women's Health Across the Nation. Psychosom Med 80:114-121
Duan, Chunzhe; Talbott, Evelyn; Brooks, Maria et al. (2018) Five-year exposure to PM2.5 and ozone and subclinical atherosclerosis in late midlife women: The Study of Women's Health Across the Nation. Int J Hyg Environ Health :
Yoshida, Kazuki; Yu, Zhi; Greendale, Gail A et al. (2018) Effects of analgesics on bone mineral density: A longitudinal analysis of the prospective SWAN cohort with three-group matching weights. Pharmacoepidemiol Drug Saf 27:182-190
Waetjen, L Elaine; Xing, Guibo; Johnson, Wesley O et al. (2018) Factors associated with reasons incontinent midlife women report for not seeking urinary incontinence treatment over 9 years across the menopausal transition. Menopause 25:29-37
Allshouse, Amanda A; Santoro, Nanette; Green, Robin et al. (2018) Religiosity and faith in relation to time to metabolic syndrome for Hispanic women in a multiethnic cohort of women-Findings from the Study of Women's Health Across the Nation (SWAN). Maturitas 112:18-23
Allshouse, Amanda; Pavlovic, Jelena; Santoro, Nanette (2018) Menstrual Cycle Hormone Changes Associated with Reproductive Aging and How They May Relate to Symptoms. Obstet Gynecol Clin North Am 45:613-628
Hanley, Carrie; Shields, Kelly J; Matthews, Karen A et al. (2018) Associations of cardiovascular fat radiodensity and vascular calcification in midlife women: The SWAN cardiovascular fat ancillary study. Atherosclerosis 279:114-121
Chyu, Laura; Upchurch, Dawn M (2018) A Longitudinal Analysis of Allostatic Load among a Multi-Ethnic Sample of Midlife Women: Findings from the Study of Women's Health Across the Nation. Womens Health Issues 28:258-266

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