With a focus on improving infection-related perinatal morbidity and mortality, 5 years ago, the University of Alabama at Birmingham (DAB) and the Aga Khan University (AKU), in Karachi, Pakistan competed for and were awarded a Research Unit within the Global Network (GN). Despite several setbacks, the UAB/AKU Collaboration has evolved into a very well-functioning and highly productive research and training program. This renewal application seeks to maintain and enhance that Global Network Research Unit (GNRU) focusing on improving developing country maternal-infant health with a specific emphasis on reducing perinatal morbidity and mortality. This GNRU will be, as before, a partnership between The Dept of OBGYN at UAB and the Dept of Community Health Sciences at AKU. The clinical subjects for studies conducted in Pakistan will include pregnant women from both urban and rural, and hospital and community-based populations. Through this study and our participation in other common protocols, we hope to stimulate the development and growth of Pakistani researchers and promote collaborations between AKU researchers and those from UAB. We also intend to attract new U.S. and Pakistani investigators to the field of international Maternal and Child Health research by systematic mentoring of promising junior investigators and recruiting senior scientists from related fields. In doing all this, we hope to enhance the research environment available to AKU scientists by providing high quality responsive administrative, statistical and research support services within a scientifically stimulating multidisciplinary setting. With the completion of these multi-centered projects, not only will we have answered some very important questions related to pregnancy and newborn outcomes in developing countries, but AKU, in partnership with UAB, will have developed a superb rural and urban perinatal-related research infrastructure, tightly linked to their developing maternal and child health care systems.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HD040607-11
Application #
8072065
Study Section
Special Emphasis Panel (ZHD1-MCHG-B (25))
Program Officer
Wright, Linda
Project Start
2001-09-03
Project End
2012-04-30
Budget Start
2011-05-01
Budget End
2012-04-30
Support Year
11
Fiscal Year
2011
Total Cost
$668,292
Indirect Cost
Name
Drexel University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
002604817
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Pasha, O; McClure, E M; Saleem, S et al. (2018) A prospective cause of death classification system for maternal deaths in low and middle-income countries: results from the Global Network Maternal Newborn Health Registry. BJOG 125:1137-1143
McClure, E M; Garces, A; Saleem, S et al. (2018) Global Network for Women's and Children's Health Research: probable causes of stillbirth in low- and middle-income countries using a prospectively defined classification system. BJOG 125:131-138
Goldenberg, Robert L; Saleem, Sarah; Ali, Sumera et al. (2017) Maternal near miss in low-resource areas. Int J Gynaecol Obstet 138:347-355
Swanson, David; Lokangaka, Adrien; Bauserman, Melissa et al. (2017) Challenges of Implementing Antenatal Ultrasound Screening in a Rural Study Site: A Case Study From the Democratic Republic of the Congo. Glob Health Sci Pract 5:315-324
Harrison, Margo S; Pasha, Omrana; Saleem, Sarah et al. (2017) A prospective study of maternal, fetal and neonatal outcomes in the setting of cesarean section in low- and middle-income countries. Acta Obstet Gynecol Scand 96:410-420
Madhani, Farhana I; Karmaliani, Rozina; Patel, Cyra et al. (2017) Women's Perceptions and Experiences of Domestic Violence: An Observational Study From Hyderabad, Pakistan. J Interpers Violence 32:76-100
Garces, Ana L; McClure, Elizabeth M; PĂ©rez, Wilton et al. (2017) The Global Network Neonatal Cause of Death algorithm for low-resource settings. Acta Paediatr 106:904-911
Klein, Karen; McClure, Elizabeth M; Colaci, Daniela et al. (2016) The Antenatal Corticosteroids Trial (ACT): a secondary analysis to explore site differences in a multi-country trial. Reprod Health 13:64
Goldenberg, Robert L; Thorsten, Vanessa R; Althabe, Fernando et al. (2016) The global network antenatal corticosteroids trial: impact on stillbirth. Reprod Health 13:68
Althabe, Fernando; Thorsten, Vanessa; Klein, Karen et al. (2016) The Antenatal Corticosteroids Trial (ACT)'s explanations for neonatal mortality - a secondary analysis. Reprod Health 13:62

Showing the most recent 10 out of 99 publications