The objective of the Administrative Core is to support the performance of the research outlined in this IPCP-HTM application. The Core will be directed by the Principal Investigator, John P. Moore, PhD, and will be located in the Department of Microbiology and Immunology at the Weill Medical College of Cornell University, New York, NY. It will coordinate all the operations of the IPCP-HTM group, and ensure that the overall goals of the research team are carried out by the Project Leaders. It will also ensure that all necessary support services are provided to the Research Project Leaders to further their work. The Chief Administrator of this Core will be Mrs. Angie Leitch, who will also act as Secretary to the Internal Steering Committee. The Core will help to obtain and maintain IACUC and IRB approvals for the work outlined in the proposal. It will coordinate the creation and maintenance of the Patent Plan, the Public Access to Data Plan, and the Sharing Research Resources Plan. The Core will facilitate the obtainment of specialist research reagents for the use of the Research Project Leaders. This will involve making any appropriate and necessary arrangements for the provision of inhibitors from corporate collaborators via Material Transfer Agreements or other legal agreements. The Core will liaise with the Internal Steering Committee and the Scientific Advisory Panel, to make arrangements for conference calls, for the annual meeting, and for any other meeting that may be called by the Principal Investigator, the Co-Principal Investigator or the Research Project Leaders. The Core will maintain a database of critical information derived from the individual research projects, particularly Research Project III, and it will assist with the publication of research papers as and when such a service is requested.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI076982-03
Application #
8075534
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
3
Fiscal Year
2010
Total Cost
$119,666
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Type
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Veazey, Ronald S; Ling, Binhua (2017) Short Communication: Comparative Susceptibility of Rhesus Macaques of Indian and Chinese Origin to Vaginal Simian-Human Immunodeficiency Virus Transmission as Models for HIV Prevention Research. AIDS Res Hum Retroviruses 33:1199-1201
Fletcher, Patricia; Herrera, Carolina; Armanasco, Naomi et al. (2016) Short Communication: Limited Anti-HIV-1 Activity of Maraviroc in Mucosal Tissues. AIDS Res Hum Retroviruses 32:334-8
Malcolm, R Karl; Lowry, Deborah; Boyd, Peter et al. (2014) Pharmacokinetics of a CCR5 inhibitor in rhesus macaques following vaginal, rectal and oral application. J Antimicrob Chemother 69:1325-9
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Fetherston, Susan M; Geer, Leslie; Veazey, Ronald S et al. (2013) Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220. J Antimicrob Chemother 68:394-403
Veazey, Ronald S (2013) Animal models for microbicide safety and efficacy testing. Curr Opin HIV AIDS 8:295-303
Malcolm, R Karl; Forbes, Claire J; Geer, Leslie et al. (2013) Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaques. J Antimicrob Chemother 68:678-83
Barouch, Dan H; Klasse, Per Johan; Dufour, Jason et al. (2012) Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission. Proc Natl Acad Sci U S A 109:8694-8
Malcolm, R Karl; Veazey, Ronald S; Geer, Leslie et al. (2012) Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques. Antimicrob Agents Chemother 56:2251-8
Dufour, Jason P; Phillippi-Falkenstein, Kathrine; Bohm, Rudolf P et al. (2012) Excision of femoral head and neck for treatment of coxofemoral degenerative joint disease in a rhesus macaque (Macaca mulatta). Comp Med 62:539-42

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