Abstract

SPATIAL SCIENCE CORE Abstract The Spatial Sciences Core (SSC) is designed to characterize the social and physical environment in regions of Southern and Central Africa where studies of the epidemiology of malaria, vector biology and parasite genomics will be conducted. The Core will provide an environmental context to better understand the drivers of malaria transmission in regions with different stages of malaria control. To extend and compliment this objective, the Spatial Science Core includes a dedicated component in the research and application of spatial statistical methods. We hypothesize that having a strong translational research component in spatial statistics will allow projects to move beyond the mapping of environment and malaria metrics to statistically linking dynamic changes in the environment to corresponding variation in malaria transmission, thus providing a sound scientific approach to identifying environmental interactions and extrapolating beyond the study areas to similar malaria transmission settings.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
2U19AI089680-08
Application #
9263241
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2017-07-01
Budget End
2018-03-31
Support Year
8
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205

  Publications

Kanyangarara, Mufaro; Hamapumbu, Harry; Mamini, Edmore et al. (2018) Malaria knowledge and bed net use in three transmission settings in southern Africa. Malar J 17:41
Zawada, Jacek W; Dahan-Moss, Yael L; Muleba, Mbanga et al. (2018) Molecular and physiological analysis of Anopheles funestus swarms in Nchelenge, Zambia. Malar J 17:49
Jones, Christine M; Lee, Yoosook; Kitchen, Andrew et al. (2018) Complete Anopheles funestus mitogenomes reveal an ancient history of mitochondrial lineages and their distribution in southern and central Africa. Sci Rep 8:9054
Pringle, Julia C; Carpi, Giovanna; Almagro-Garcia, Jacob et al. (2018) RTS,S/AS01 malaria vaccine mismatch observed among Plasmodium falciparum isolates from southern and central Africa and globally. Sci Rep 8:6622
Searle, Kelly M; Lubinda, Jailos; Hamapumbu, Harry et al. (2017) Characterizing and quantifying human movement patterns using GPS data loggers in an area approaching malaria elimination in rural southern Zambia. R Soc Open Sci 4:170046
Searle, Kelly M; Katowa, Ben; Kobayashi, Tamaki et al. (2017) Distinct parasite populations infect individuals identified through passive and active case detection in a region of declining malaria transmission in southern Zambia. Malar J 16:154
Gibson, Lauren E; Markwalter, Christine F; Kimmel, Danielle W et al. (2017) Plasmodium falciparum HRP2 ELISA for analysis of dried blood spot samples in rural Zambia. Malar J 16:350
Ippolito, Matthew M; Searle, Kelly M; Hamapumbu, Harry et al. (2017) House Structure Is Associated with Plasmodium falciparum Infection in a Low-Transmission Setting in Southern Zambia. Am J Trop Med Hyg 97:1561-1567
Sutcliffe, Catherine G; Searle, Kelly; Matakala, Hellen K et al. (2017) Measles and Rubella Seroprevalence Among HIV-infected and Uninfected Zambian Youth. Pediatr Infect Dis J 36:301-306
Das, Smita; Muleba, Mbanga; Stevenson, Jennifer C et al. (2017) Beyond the entomological inoculation rate: characterizing multiple blood feeding behavior and Plasmodium falciparum multiplicity of infection in Anopheles mosquitoes in northern Zambia. Parasit Vectors 10:45

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