While there has been progress in developing an AIDS vaccine, there is as yet no truly effective vaccine to prevent HIV-1 transmission. This project will provide tissue analysis technologies such as in situ hybridization and tetramer staining, immunochemistry, and combinations thereof to investigators who will use these methods to assess impact and mechanisms of vaccine strategies on the natural history of vaginal transmission and acute systemic infection in the SlV/SHIV-rhesus macaque animal model.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI095985-01
Application #
8198154
Study Section
Special Emphasis Panel (ZAI1-LR-A (M2))
Project Start
2011-07-15
Project End
2016-06-30
Budget Start
2011-07-15
Budget End
2012-06-30
Support Year
1
Fiscal Year
2011
Total Cost
$509,675
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215
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