Young men who have sex with men (YMSM) in the U.S. have a disproportionally higher incidence of Human Immunodeficiency Virus (HIV) and other sexually transmitted infections (STIs) compared with other MSM. These men also have low uptake of HIV/STI testing and pre-exposure prophylaxis (PrEP), a highly efficacious HIV prevention strategy when taken daily. Known barriers include low perceived HIV risk, difficulty accessing providers, lack of engagement in regular healthcare, stigma, and concerns about confidentiality. The high uptake of mobile devices among youth provides an opportunity to leverage mobile health applications on hand- held devices (mHealth) to increase HIV/STI testing and PrEP uptake among YMSM. The major goals of this pilot project are to refine and pilot test a combination mobile app based intervention designed to overcome barriers to HIV/STI testing and PrEP uptake among YMSM. Using qualitative methods and informed by the Information, Motivation, and Behavioral Skills theoretical model, we will build upon an existing mobile app platform to develop and tailor the mobile app, LYNX, to increase both HIV/STI testing and PrEP uptake among YMSM through an iterative development design method (aim 1). We will then pilot test this mobile app for usability in a 2-month open technical pilot (aim 2). After revising this app, we will subsequently conduct a 6-month pilot randomized controlled trial to evaluate the acceptability and feasibility of LYNX among a diverse sample of YMSM in Chicago, IL and Tampa, FL. Upon completion of this 2-year project, we will have optimized the LYNX mobile app for increasing HIV/STI testing and PrEP uptake among YMSM, which will be poised for further evaluation in a full-scale efficacy trial in years 3-5 of the iTech.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19HD089881-01
Application #
9207247
Study Section
Special Emphasis Panel (ZHD1-DSR-N (50)1)
Project Start
Project End
Budget Start
2016-09-01
Budget End
2017-05-31
Support Year
1
Fiscal Year
2016
Total Cost
$197,925
Indirect Cost
$19,292
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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Mulawa, Marta I; LeGrand, Sara; Hightow-Weidman, Lisa B (2018) eHealth to Enhance Treatment Adherence Among Youth Living with HIV. Curr HIV/AIDS Rep 15:336-349
Bauermeister, José A; Golinkoff, Jesse M; Horvath, Keith J et al. (2018) A Multilevel Tailored Web App-Based Intervention for Linking Young Men Who Have Sex With Men to Quality Care (Get Connected): Protocol for a Randomized Controlled Trial. JMIR Res Protoc 7:e10444
Hurt, Christopher B (2018) PrEParing Providers: The Next Challenge in Implementing Human Immunodeficiency Virus Preexposure Prophylaxis. Sex Transm Dis 45:459-461
Hightow-Weidman, Lisa B; Muessig, Kathryn; Rosenberg, Eli et al. (2018) University of North Carolina/Emory Center for Innovative Technology (iTech) for Addressing the HIV Epidemic Among Adolescents and Young Adults in the United States: Protocol and Rationale for Center Development. JMIR Res Protoc 7:e10365
Hurt, Christopher B (2018) PrEParing Providers: The Next Challenge in Implementing HIV Pre-Exposure Prophylaxis. Sex Transm Dis :
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LeGrand, Sara; Muessig, Kathryn E; Horvath, Keith J et al. (2017) Using technology to support HIV self-testing among MSM. Curr Opin HIV AIDS 12:425-431
Hightow-Weidman, Lisa B; Muessig, Kathryn E; Bauermeister, José A et al. (2017) The future of digital games for HIV prevention and care. Curr Opin HIV AIDS 12:501-507
Bauermeister, José A; Golinkoff, Jesse M; Muessig, Kathryn E et al. (2017) Addressing engagement in technology-based behavioural HIV interventions through paradata metrics. Curr Opin HIV AIDS 12:442-446

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